node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1QL2 | C1QL4 | ENSP00000272520 | ENSP00000335285 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). | Complement C1q-like protein 4; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). May inhibit adipocyte differentiation at an early stage of the process (By similarity). | 0.404 |
C1QL2 | YPEL1 | ENSP00000272520 | ENSP00000342832 | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family. | 0.421 |
C1QL4 | C1QL2 | ENSP00000335285 | ENSP00000272520 | Complement C1q-like protein 4; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). May inhibit adipocyte differentiation at an early stage of the process (By similarity). | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). | 0.404 |
C1QL4 | WDR26 | ENSP00000335285 | ENSP00000498603 | Complement C1q-like protein 4; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). May inhibit adipocyte differentiation at an early stage of the process (By similarity). | WD repeat-containing protein 26; G-beta-like protein involved in cell signal transduction. Acts as a negative regulator in MAPK signaling pathway. Functions as a scaffolding protein to promote G beta:gamma-mediated PLCB2 plasma membrane translocation and subsequent activation in leukocytes. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a negative regulator of the canonical Wnt signaling pathway through preventing ubi [...] | 0.454 |
C1QL4 | YPEL1 | ENSP00000335285 | ENSP00000342832 | Complement C1q-like protein 4; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). May inhibit adipocyte differentiation at an early stage of the process (By similarity). | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family. | 0.505 |
CTTNBP2NL | STRN3 | ENSP00000271277 | ENSP00000350071 | CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like. | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein. | 0.999 |
CTTNBP2NL | STRN4 | ENSP00000271277 | ENSP00000375777 | CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like. | Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | 0.998 |
CTTNBP2NL | YPEL1 | ENSP00000271277 | ENSP00000342832 | CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like. | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family. | 0.574 |
FBXL2 | YPEL1 | ENSP00000417601 | ENSP00000342832 | F-box/LRR-repeat protein 2; Calcium-activated substrate recognition component of the SCF (SKP1-cullin-F-box protein) E3 ubiquitin-protein ligase complex, SCF(FBXL2), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Unlike many F-box proteins, FBXL2 does not seem to target phosphodegron within its substrates but rather calmodulin-binding motifs and is thereby antagonized by calmodulin. This is the case for the cyclins CCND2 and CCND3 which polyubiquitination and subsequent degradation are inhibited by calmodulin. Through CCND2 and CCND3 degrad [...] | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family. | 0.624 |
FBXL20 | YPEL1 | ENSP00000264658 | ENSP00000342832 | F-box/LRR-repeat protein 20; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission (By similarity). | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family. | 0.511 |
NCAM1 | YPEL1 | ENSP00000480132 | ENSP00000342832 | Neural cell adhesion molecule 1; This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family. | 0.416 |
STRN3 | CTTNBP2NL | ENSP00000350071 | ENSP00000271277 | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein. | CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like. | 0.999 |
STRN3 | STRN4 | ENSP00000350071 | ENSP00000375777 | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein. | Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | 0.999 |
STRN3 | YPEL1 | ENSP00000350071 | ENSP00000342832 | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein. | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family. | 0.589 |
STRN4 | CTTNBP2NL | ENSP00000375777 | ENSP00000271277 | Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | CTTNBP2 N-terminal-like protein; CTTNBP2 N-terminal like. | 0.998 |
STRN4 | STRN3 | ENSP00000375777 | ENSP00000350071 | Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein. | 0.999 |
STRN4 | YPEL1 | ENSP00000375777 | ENSP00000342832 | Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family. | 0.545 |
WDR26 | C1QL4 | ENSP00000498603 | ENSP00000335285 | WD repeat-containing protein 26; G-beta-like protein involved in cell signal transduction. Acts as a negative regulator in MAPK signaling pathway. Functions as a scaffolding protein to promote G beta:gamma-mediated PLCB2 plasma membrane translocation and subsequent activation in leukocytes. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a negative regulator of the canonical Wnt signaling pathway through preventing ubi [...] | Complement C1q-like protein 4; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). May inhibit adipocyte differentiation at an early stage of the process (By similarity). | 0.454 |
WDR26 | YPEL1 | ENSP00000498603 | ENSP00000342832 | WD repeat-containing protein 26; G-beta-like protein involved in cell signal transduction. Acts as a negative regulator in MAPK signaling pathway. Functions as a scaffolding protein to promote G beta:gamma-mediated PLCB2 plasma membrane translocation and subsequent activation in leukocytes. Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a negative regulator of the canonical Wnt signaling pathway through preventing ubi [...] | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family. | 0.630 |
YPEL1 | C1QL2 | ENSP00000342832 | ENSP00000272520 | Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family. | Complement C1q-like protein 2; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity). | 0.421 |