STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYNGR4Synaptogyrin-4; Synaptogyrin 4. (234 aa)    
Predicted Functional Partners:
PLEKHB1
Pleckstrin homology domain containing B1.
      
 0.646
TEX26
Testis-expressed protein 26; Testis expressed 26.
      
 0.643
FNDC8
Fibronectin type III domain containing 8.
   
  
 0.607
ZNF681
Zinc finger protein 681; May be involved in transcriptional regulation.
      
 0.471
OR13J1
Olfactory receptor 13J1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.468
DENND4A
C-myc promoter-binding protein; Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. According to it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter.
      
 0.466
PROSER2
Proline and serine rich 2.
      
 0.460
TMEM143
Transmembrane protein 143.
   
  
 0.460
THEM6
Protein THEM6; Thioesterase superfamily member 6.
      
 0.454
TMEM220
Transmembrane protein 220.
      
 0.449
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.