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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC43Leucine-rich repeat-containing protein 43; Leucine rich repeat containing 43. (656 aa)    
Predicted Functional Partners:
TEX43
Testis-expressed protein 43; Testis expressed 43.
      
 0.688
CFAP47
Cilia and flagella associated protein 47.
   
 
 0.646
FAM181A
Protein FAM181A; Family with sequence similarity 181 member A.
   
  
 0.609
UBXN10
UBX domain-containing protein 10; VCP/p97-binding protein required for ciliogenesis. Acts as a tethering factor that facilitates recruitment of VCP/p97 to the intraflagellar transport complex B (IFT- B) in cilia. UBX domain-containing proteins act as tethering factors for VCP/p97 and may specify substrate specificity of VCP/p97 ; Belongs to the UBXN10 family.
   
    0.607
C1orf189
Uncharacterized protein C1orf189; Chromosome 1 open reading frame 189.
      
 0.582
DYDC1
DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis.
   
 
 0.578
ANKRD60
Ankyrin repeat domain 60.
    
 
 0.572
LRRC46
Leucine-rich repeat-containing protein 46; Leucine rich repeat containing 46.
   
 
  0.560
PPP1R3F
Protein phosphatase 1 regulatory subunit 3F; Glycogen-targeting subunit for protein phosphatase 1 (PP1).
     
 0.554
PPP1R3C
Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in a variety of cell types.
     
 0.554
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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