FAM47A protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C13orf42	CCDC166	ENSP00000490517	ENSP00000437468	Uncharacterized protein C13orf42; Chromosome 13 open reading frame 42.	Coiled-coil domain containing 166.	0.466
C13orf42	FAM47A	ENSP00000490517	ENSP00000345029	Uncharacterized protein C13orf42; Chromosome 13 open reading frame 42.	Protein FAM47A; Family with sequence similarity 47 member A.	0.425
C13orf42	TCP10	ENSP00000490517	ENSP00000484621	Uncharacterized protein C13orf42; Chromosome 13 open reading frame 42.	T-complex protein 10A homolog.	0.400
CCDC166	C13orf42	ENSP00000437468	ENSP00000490517	Coiled-coil domain containing 166.	Uncharacterized protein C13orf42; Chromosome 13 open reading frame 42.	0.466
CCDC166	FAM47A	ENSP00000437468	ENSP00000345029	Coiled-coil domain containing 166.	Protein FAM47A; Family with sequence similarity 47 member A.	0.410
ERVW-1	FAM47A	ENSP00000419945	ENSP00000345029	Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5.	Protein FAM47A; Family with sequence similarity 47 member A.	0.435
ERVW-1	NBPF15	ENSP00000419945	ENSP00000462600	Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5.	Neuroblastoma breakpoint family member 15; NBPF member 15.	0.411
ERVW-1	NBPF3	ENSP00000419945	ENSP00000316782	Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5.	Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family.	0.439
FAM47A	C13orf42	ENSP00000345029	ENSP00000490517	Protein FAM47A; Family with sequence similarity 47 member A.	Uncharacterized protein C13orf42; Chromosome 13 open reading frame 42.	0.425
FAM47A	CCDC166	ENSP00000345029	ENSP00000437468	Protein FAM47A; Family with sequence similarity 47 member A.	Coiled-coil domain containing 166.	0.410
FAM47A	ERVW-1	ENSP00000345029	ENSP00000419945	Protein FAM47A; Family with sequence similarity 47 member A.	Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5.	0.435
FAM47A	LANCL3	ENSP00000345029	ENSP00000367882	Protein FAM47A; Family with sequence similarity 47 member A.	LanC-like protein 3; LanC like 3.	0.450
FAM47A	NBPF15	ENSP00000345029	ENSP00000462600	Protein FAM47A; Family with sequence similarity 47 member A.	Neuroblastoma breakpoint family member 15; NBPF member 15.	0.414
FAM47A	NBPF3	ENSP00000345029	ENSP00000316782	Protein FAM47A; Family with sequence similarity 47 member A.	Neuroblastoma breakpoint family member 3; NBPF member 3; Belongs to the NBPF family.	0.456
FAM47A	NBPF4	ENSP00000345029	ENSP00000389237	Protein FAM47A; Family with sequence similarity 47 member A.	Neuroblastoma breakpoint family member 4; NBPF member 4.	0.422
FAM47A	PRAMEF2	ENSP00000345029	ENSP00000240189	Protein FAM47A; Family with sequence similarity 47 member A.	PRAME family member 2; Belongs to the PRAME family.	0.490
FAM47A	RNF123	ENSP00000345029	ENSP00000328287	Protein FAM47A; Family with sequence similarity 47 member A.	E3 ubiquitin-protein ligase RNF123; Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Promotes the ubiquitination and proteasome- mediated degradation of CDKN1B which is the cyclin-dependent kinase inhibitor at the G0-G1 transition of the cell cycle. Functions also as an inhibitor of innate antiviral signaling mediated by DDX58 and IFIH1 independently of its E3 ligase activity. Interacts with the N-terminal CARD domains of DDX58 and IFIH1 and competes with the downstream adapter MAVS.	0.457
FAM47A	TCP10	ENSP00000345029	ENSP00000484621	Protein FAM47A; Family with sequence similarity 47 member A.	T-complex protein 10A homolog.	0.431
LANCL3	FAM47A	ENSP00000367882	ENSP00000345029	LanC-like protein 3; LanC like 3.	Protein FAM47A; Family with sequence similarity 47 member A.	0.450
NBPF15	ERVW-1	ENSP00000462600	ENSP00000419945	Neuroblastoma breakpoint family member 15; NBPF member 15.	Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5.	0.411