node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDH18 | TMEM215 | ENSP00000371710 | ENSP00000345468 | Cadherin-18; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. | Transmembrane protein 215. | 0.658 |
FAM219A | TMEM215 | ENSP00000499069 | ENSP00000345468 | Protein FAM219A; Family with sequence similarity 219 member A. | Transmembrane protein 215. | 0.418 |
GABRQ | TMEM215 | ENSP00000469332 | ENSP00000345468 | Gamma-aminobutyric acid receptor subunit theta; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. | Transmembrane protein 215. | 0.462 |
PRDM8 | TMEM215 | ENSP00000339764 | ENSP00000345468 | PR domain zinc finger protein 8; Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity); Belongs to the class V-like SAM-binding methyltrans [...] | Transmembrane protein 215. | 0.457 |
PRDM8 | VSX1 | ENSP00000339764 | ENSP00000365899 | PR domain zinc finger protein 8; Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity); Belongs to the class V-like SAM-binding methyltrans [...] | Visual system homeobox 1; Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development. Dispensable in early retinal development (By similarity); Belongs to the paired homeobox family. | 0.523 |
TANC1 | TMEM215 | ENSP00000263635 | ENSP00000345468 | Protein TANC1; May be a scaffold component in the postsynaptic density. | Transmembrane protein 215. | 0.400 |
THAP2 | TMEM215 | ENSP00000310796 | ENSP00000345468 | THAP domain containing 2. | Transmembrane protein 215. | 0.432 |
TMEM215 | CDH18 | ENSP00000345468 | ENSP00000371710 | Transmembrane protein 215. | Cadherin-18; Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. | 0.658 |
TMEM215 | FAM219A | ENSP00000345468 | ENSP00000499069 | Transmembrane protein 215. | Protein FAM219A; Family with sequence similarity 219 member A. | 0.418 |
TMEM215 | GABRQ | ENSP00000345468 | ENSP00000469332 | Transmembrane protein 215. | Gamma-aminobutyric acid receptor subunit theta; GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. | 0.462 |
TMEM215 | PRDM8 | ENSP00000345468 | ENSP00000339764 | Transmembrane protein 215. | PR domain zinc finger protein 8; Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity); Belongs to the class V-like SAM-binding methyltrans [...] | 0.457 |
TMEM215 | TANC1 | ENSP00000345468 | ENSP00000263635 | Transmembrane protein 215. | Protein TANC1; May be a scaffold component in the postsynaptic density. | 0.400 |
TMEM215 | THAP2 | ENSP00000345468 | ENSP00000310796 | Transmembrane protein 215. | THAP domain containing 2. | 0.432 |
TMEM215 | VSX1 | ENSP00000345468 | ENSP00000365899 | Transmembrane protein 215. | Visual system homeobox 1; Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development. Dispensable in early retinal development (By similarity); Belongs to the paired homeobox family. | 0.515 |
TMEM215 | ZSWIM1 | ENSP00000345468 | ENSP00000361601 | Transmembrane protein 215. | Zinc finger SWIM-type containing 1. | 0.413 |
VSX1 | PRDM8 | ENSP00000365899 | ENSP00000339764 | Visual system homeobox 1; Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development. Dispensable in early retinal development (By similarity); Belongs to the paired homeobox family. | PR domain zinc finger protein 8; Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity); Belongs to the class V-like SAM-binding methyltrans [...] | 0.523 |
VSX1 | TMEM215 | ENSP00000365899 | ENSP00000345468 | Visual system homeobox 1; Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development. Dispensable in early retinal development (By similarity); Belongs to the paired homeobox family. | Transmembrane protein 215. | 0.515 |
ZSWIM1 | TMEM215 | ENSP00000361601 | ENSP00000345468 | Zinc finger SWIM-type containing 1. | Transmembrane protein 215. | 0.413 |