HRCT1 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Export your current network:

... as a bitmap image:

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file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC177	HRCT1	ENSP00000469474	ENSP00000346283	Coiled-coil domain containing 177.	Histidine rich carboxyl terminus 1.	0.513
CCDC177	MYO15B	ENSP00000469474	ENSP00000495242	Coiled-coil domain containing 177.	Unconventional myosin-XVB; Unknown, due to the absence of a functional motor domain.	0.498
HRCT1	CCDC177	ENSP00000346283	ENSP00000469474	Histidine rich carboxyl terminus 1.	Coiled-coil domain containing 177.	0.513
HRCT1	MYO15B	ENSP00000346283	ENSP00000495242	Histidine rich carboxyl terminus 1.	Unconventional myosin-XVB; Unknown, due to the absence of a functional motor domain.	0.500
HRCT1	OR4L1	ENSP00000346283	ENSP00000319217	Histidine rich carboxyl terminus 1.	Olfactory receptor 4L1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	0.451
HRCT1	SPAAR	ENSP00000346283	ENSP00000490187	Histidine rich carboxyl terminus 1.	Small regulatory polypeptide of amino acid response; [Isoform 2]: Negative regulator of amino acid sensing and mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels and amino acids. Negatively regulates mTORC1 activation by inhibiting recruitment of mTORC1 to lysosomes upon stimulation with amino acids: acts by promoting the formation of a tightly bound supercomplex composed of the lysosomal V- ATPase, Ragulator and Rag GTPases, preventing recruitment of mTORC1. Acts as a regulator of muscle regeneration following injury by regulating mTORC1 act [...]	0.575
HRCT1	TMEM141	ENSP00000346283	ENSP00000290079	Histidine rich carboxyl terminus 1.	Transmembrane protein 141.	0.403
MYO15B	CCDC177	ENSP00000495242	ENSP00000469474	Unconventional myosin-XVB; Unknown, due to the absence of a functional motor domain.	Coiled-coil domain containing 177.	0.498
MYO15B	HRCT1	ENSP00000495242	ENSP00000346283	Unconventional myosin-XVB; Unknown, due to the absence of a functional motor domain.	Histidine rich carboxyl terminus 1.	0.500
OR4L1	HRCT1	ENSP00000319217	ENSP00000346283	Olfactory receptor 4L1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	Histidine rich carboxyl terminus 1.	0.451
SPAAR	HRCT1	ENSP00000490187	ENSP00000346283	Small regulatory polypeptide of amino acid response; [Isoform 2]: Negative regulator of amino acid sensing and mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels and amino acids. Negatively regulates mTORC1 activation by inhibiting recruitment of mTORC1 to lysosomes upon stimulation with amino acids: acts by promoting the formation of a tightly bound supercomplex composed of the lysosomal V- ATPase, Ragulator and Rag GTPases, preventing recruitment of mTORC1. Acts as a regulator of muscle regeneration following injury by regulating mTORC1 act [...]	Histidine rich carboxyl terminus 1.	0.575
TMEM141	HRCT1	ENSP00000290079	ENSP00000346283	Transmembrane protein 141.	Histidine rich carboxyl terminus 1.	0.403