node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRL1 | LRRIQ3 | ENSP00000340688 | ENSP00000346414 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | Leucine rich repeats and IQ motif containing 3. | 0.514 |
ADGRL2 | LRRIQ3 | ENSP00000359765 | ENSP00000346414 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine rich repeats and IQ motif containing 3. | 0.517 |
ADGRL3 | LRRIQ3 | ENSP00000422533 | ENSP00000346414 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Leucine rich repeats and IQ motif containing 3. | 0.514 |
FAM227B | FPGT | ENSP00000299338 | ENSP00000359935 | Protein FAM227B; Family with sequence similarity 227 member B. | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | 0.511 |
FAM227B | LRRIQ3 | ENSP00000299338 | ENSP00000346414 | Protein FAM227B; Family with sequence similarity 227 member B. | Leucine rich repeats and IQ motif containing 3. | 0.734 |
FPGT | FAM227B | ENSP00000359935 | ENSP00000299338 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | Protein FAM227B; Family with sequence similarity 227 member B. | 0.511 |
FPGT | LRRIQ3 | ENSP00000359935 | ENSP00000346414 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | Leucine rich repeats and IQ motif containing 3. | 0.736 |
FPGT | TNNI3K | ENSP00000359935 | ENSP00000322251 | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.804 |
FPGT-TNNI3K | LRRIQ3 | ENSP00000450895 | ENSP00000346414 | FPGT-TNNI3K readthrough. | Leucine rich repeats and IQ motif containing 3. | 0.649 |
FPGT-TNNI3K | TNNI3K | ENSP00000450895 | ENSP00000322251 | FPGT-TNNI3K readthrough. | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.902 |
FRMD3 | LRRIQ3 | ENSP00000303508 | ENSP00000346414 | FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. | Leucine rich repeats and IQ motif containing 3. | 0.645 |
FRMD3 | SAMD5 | ENSP00000303508 | ENSP00000356444 | FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. | Sterile alpha motif domain containing 5. | 0.616 |
FRMD3 | TMC7 | ENSP00000303508 | ENSP00000455041 | FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. | Transmembrane channel-like protein 7; Probable ion channel. | 0.612 |
LRRIQ3 | ADGRL1 | ENSP00000346414 | ENSP00000340688 | Leucine rich repeats and IQ motif containing 3. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | 0.514 |
LRRIQ3 | ADGRL2 | ENSP00000346414 | ENSP00000359765 | Leucine rich repeats and IQ motif containing 3. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.517 |
LRRIQ3 | ADGRL3 | ENSP00000346414 | ENSP00000422533 | Leucine rich repeats and IQ motif containing 3. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | 0.514 |
LRRIQ3 | FAM227B | ENSP00000346414 | ENSP00000299338 | Leucine rich repeats and IQ motif containing 3. | Protein FAM227B; Family with sequence similarity 227 member B. | 0.734 |
LRRIQ3 | FPGT | ENSP00000346414 | ENSP00000359935 | Leucine rich repeats and IQ motif containing 3. | Fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids. | 0.736 |
LRRIQ3 | FPGT-TNNI3K | ENSP00000346414 | ENSP00000450895 | Leucine rich repeats and IQ motif containing 3. | FPGT-TNNI3K readthrough. | 0.649 |
LRRIQ3 | FRMD3 | ENSP00000346414 | ENSP00000303508 | Leucine rich repeats and IQ motif containing 3. | FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer. | 0.645 |