node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BTBD9 | ZBTB45 | ENSP00000418751 | ENSP00000346603 | BTB/POZ domain-containing protein 9; BTB domain containing 9. | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.451 |
CPTP | GPR137 | ENSP00000343890 | ENSP00000411827 | Ceramide-1-phosphate transfer protein; Mediates the intracellular transfer of ceramide-1-phosphate (C1P) between organelle membranes and the cell membrane. Required for normal structure of the Golgi stacks. Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). Plays a role in the regulation of the cellular levels of ceramide-1- phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity [...] | Integral membrane protein GPR137; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. May play a role in autophagy ; Belongs to the GPR137 family. | 0.463 |
CPTP | ZBTB45 | ENSP00000343890 | ENSP00000346603 | Ceramide-1-phosphate transfer protein; Mediates the intracellular transfer of ceramide-1-phosphate (C1P) between organelle membranes and the cell membrane. Required for normal structure of the Golgi stacks. Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). Plays a role in the regulation of the cellular levels of ceramide-1- phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity [...] | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.482 |
FAM185A | ZBTB45 | ENSP00000395340 | ENSP00000346603 | Protein FAM185A; Family with sequence similarity 185 member A. | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.521 |
GPR137 | CPTP | ENSP00000411827 | ENSP00000343890 | Integral membrane protein GPR137; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. May play a role in autophagy ; Belongs to the GPR137 family. | Ceramide-1-phosphate transfer protein; Mediates the intracellular transfer of ceramide-1-phosphate (C1P) between organelle membranes and the cell membrane. Required for normal structure of the Golgi stacks. Can bind phosphoceramides with a variety of aliphatic chains, but has a preference for lipids with saturated C16:0 or monounsaturated C18:1 aliphatic chains, and is inefficient with phosphoceramides containing lignoceryl (C24:0). Plays a role in the regulation of the cellular levels of ceramide-1- phosphate, and thereby contributes to the regulation of phospholipase PLA2G4A activity [...] | 0.463 |
GPR137 | ZBTB45 | ENSP00000411827 | ENSP00000346603 | Integral membrane protein GPR137; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. May play a role in autophagy ; Belongs to the GPR137 family. | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.457 |
INAFM1 | RPUSD1 | ENSP00000447679 | ENSP00000455026 | Putative transmembrane protein INAFM1; InaF motif containing 1. | RNA pseudouridine synthase domain containing 1; Belongs to the pseudouridine synthase RluA family. | 0.434 |
INAFM1 | UBALD1 | ENSP00000447679 | ENSP00000283474 | Putative transmembrane protein INAFM1; InaF motif containing 1. | UBA-like domain-containing protein 1; UBA like domain containing 1. | 0.492 |
INAFM1 | ZBTB45 | ENSP00000447679 | ENSP00000346603 | Putative transmembrane protein INAFM1; InaF motif containing 1. | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.472 |
RPUSD1 | INAFM1 | ENSP00000455026 | ENSP00000447679 | RNA pseudouridine synthase domain containing 1; Belongs to the pseudouridine synthase RluA family. | Putative transmembrane protein INAFM1; InaF motif containing 1. | 0.434 |
RPUSD1 | UBALD1 | ENSP00000455026 | ENSP00000283474 | RNA pseudouridine synthase domain containing 1; Belongs to the pseudouridine synthase RluA family. | UBA-like domain-containing protein 1; UBA like domain containing 1. | 0.428 |
RPUSD1 | ZBTB45 | ENSP00000455026 | ENSP00000346603 | RNA pseudouridine synthase domain containing 1; Belongs to the pseudouridine synthase RluA family. | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.554 |
RPUSD1 | ZNF668 | ENSP00000455026 | ENSP00000442573 | RNA pseudouridine synthase domain containing 1; Belongs to the pseudouridine synthase RluA family. | Zinc finger protein 668; May be involved in transcriptional regulation. | 0.530 |
SLC35G4 | ZBTB45 | ENSP00000490812 | ENSP00000346603 | Solute carrier family 35 member G4. | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.479 |
UBALD1 | INAFM1 | ENSP00000283474 | ENSP00000447679 | UBA-like domain-containing protein 1; UBA like domain containing 1. | Putative transmembrane protein INAFM1; InaF motif containing 1. | 0.492 |
UBALD1 | RPUSD1 | ENSP00000283474 | ENSP00000455026 | UBA-like domain-containing protein 1; UBA like domain containing 1. | RNA pseudouridine synthase domain containing 1; Belongs to the pseudouridine synthase RluA family. | 0.428 |
UBALD1 | ZBTB45 | ENSP00000283474 | ENSP00000346603 | UBA-like domain-containing protein 1; UBA like domain containing 1. | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.560 |
WDR24 | ZBTB45 | ENSP00000293883 | ENSP00000346603 | GATOR complex protein WDR24; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux. Belongs to the WD repeat WDR24 family. | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.633 |
WDR24 | ZNF668 | ENSP00000293883 | ENSP00000442573 | GATOR complex protein WDR24; As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex. It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1. In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux. Belongs to the WD repeat WDR24 family. | Zinc finger protein 668; May be involved in transcriptional regulation. | 0.535 |
ZBTB45 | BTBD9 | ENSP00000346603 | ENSP00000418751 | Zinc finger and BTB domain-containing protein 45; May be involved in transcriptional regulation (Probable). In the central nervous system, may play a role in glial cell differentiation (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family. | BTB/POZ domain-containing protein 9; BTB domain containing 9. | 0.451 |