node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BBOF1 | GPR160 | ENSP00000377577 | ENSP00000348161 | Basal body-orientation factor 1; Basal body protein required in multiciliate cells to align and maintain cilia orientation in response to flow. May act by mediating a maturation step that stabilizes and aligns cilia orientation. Not required to respond to planar cell polarity (PCP) or flow-based orientation cues (By similarity); Belongs to the BBOF1 family. | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.448 |
CARTPT | GPR160 | ENSP00000296777 | ENSP00000348161 | Cocaine- and amphetamine-regulated transcript protein; Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro. | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.547 |
GPR142 | GPR160 | ENSP00000335158 | ENSP00000348161 | Probable G-protein coupled receptor 142; Orphan receptor. | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.535 |
GPR160 | BBOF1 | ENSP00000348161 | ENSP00000377577 | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Basal body-orientation factor 1; Basal body protein required in multiciliate cells to align and maintain cilia orientation in response to flow. May act by mediating a maturation step that stabilizes and aligns cilia orientation. Not required to respond to planar cell polarity (PCP) or flow-based orientation cues (By similarity); Belongs to the BBOF1 family. | 0.448 |
GPR160 | CARTPT | ENSP00000348161 | ENSP00000296777 | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Cocaine- and amphetamine-regulated transcript protein; Satiety factor closely associated with the actions of leptin and neuropeptide y; this anorectic peptide inhibits both normal and starvation-induced feeding and completely blocks the feeding response induced by neuropeptide Y and regulated by leptin in the hypothalamus. It promotes neuronal development and survival in vitro. | 0.547 |
GPR160 | GPR142 | ENSP00000348161 | ENSP00000335158 | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Probable G-protein coupled receptor 142; Orphan receptor. | 0.535 |
GPR160 | GPR173 | ENSP00000348161 | ENSP00000331600 | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Probable G-protein coupled receptor 173; Is a receptor for the SMIM20 derived peptides Phoenixin-14 and Phoenixin-20 (By similarity). It mediates the Phoenixin-14 and Phoenixin-20 augmentation of gonadotropin-releasing hormone (GNRH) signaling in the hypothalamus and pituitary gland (By similarity). In the ovary, it mediates the effects of Phoenixin-14 and Phoenixin-20 induced granulosa cell proliferation during follicular growth. | 0.441 |
GPR160 | KLHL8 | ENSP00000348161 | ENSP00000273963 | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN. | 0.454 |
GPR160 | MYNN | ENSP00000348161 | ENSP00000326240 | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Myoneurin. | 0.440 |
GPR160 | OTOS | ENSP00000348161 | ENSP00000375849 | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Otospiralin; May be essential for the survival of the neurosensory epithelium of the inner ear. | 0.468 |
GPR160 | SAMD7 | ENSP00000348161 | ENSP00000391299 | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Sterile alpha motif domain-containing protein 7; Involved in the regulation of gene expression in the retina. It functions as a negative regulator of CRX-controlled genes. | 0.529 |
GPR160 | SEC62 | ENSP00000348161 | ENSP00000337688 | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Translocation protein SEC62; Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER). Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen. | 0.577 |
GPR160 | TMEM45B | ENSP00000348161 | ENSP00000281441 | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Transmembrane protein 45B. | 0.466 |
GPR173 | GPR160 | ENSP00000331600 | ENSP00000348161 | Probable G-protein coupled receptor 173; Is a receptor for the SMIM20 derived peptides Phoenixin-14 and Phoenixin-20 (By similarity). It mediates the Phoenixin-14 and Phoenixin-20 augmentation of gonadotropin-releasing hormone (GNRH) signaling in the hypothalamus and pituitary gland (By similarity). In the ovary, it mediates the effects of Phoenixin-14 and Phoenixin-20 induced granulosa cell proliferation during follicular growth. | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.441 |
KLHL8 | GPR160 | ENSP00000273963 | ENSP00000348161 | Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN. | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.454 |
MYNN | GPR160 | ENSP00000326240 | ENSP00000348161 | Myoneurin. | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.440 |
OTOS | GPR160 | ENSP00000375849 | ENSP00000348161 | Otospiralin; May be essential for the survival of the neurosensory epithelium of the inner ear. | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.468 |
OTOS | SAMD7 | ENSP00000375849 | ENSP00000391299 | Otospiralin; May be essential for the survival of the neurosensory epithelium of the inner ear. | Sterile alpha motif domain-containing protein 7; Involved in the regulation of gene expression in the retina. It functions as a negative regulator of CRX-controlled genes. | 0.485 |
OTOS | SEC62 | ENSP00000375849 | ENSP00000337688 | Otospiralin; May be essential for the survival of the neurosensory epithelium of the inner ear. | Translocation protein SEC62; Mediates post-translational transport of precursor polypeptides across endoplasmic reticulum (ER). Proposed to act as a targeting receptor for small presecretory proteins containing short and apolar signal peptides. Targets and properly positions newly synthesized presecretory proteins into the SEC61 channel-forming translocon complex, triggering channel opening for polypeptide translocation to the ER lumen. | 0.420 |
SAMD7 | GPR160 | ENSP00000391299 | ENSP00000348161 | Sterile alpha motif domain-containing protein 7; Involved in the regulation of gene expression in the retina. It functions as a negative regulator of CRX-controlled genes. | Probable G-protein coupled receptor 160; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.529 |