STRINGSTRING
BTN3A2 protein (human) - STRING interaction network
"BTN3A2" - Butyrophilin subfamily 3 member A2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTN3A2Butyrophilin subfamily 3 member A2; Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells; Belongs to the immunoglobulin superfamily. BTN/MOG family (334 aa)    
Predicted Functional Partners:
BTN3A1
Butyrophilin subfamily 3 member A1; Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells toward infected and transformed cells that are characterized by high levels of phosphorylated metabolites, such as isopentenyl pyrophosphate; Butyrophilins (513 aa)
     
 
0.928
BTN3A3
Butyrophilin subfamily 3 member A3; Plays a role in T-cell responses in the adaptive immune response; Belongs to the immunoglobulin superfamily. BTN/MOG family (584 aa)
     
 
0.847
IPP
Actin-binding protein IPP; May play a role in organizing the actin cytoskeleton; BTB domain containing (584 aa)
     
   
  0.781
PPL
Periplakin; Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling; Belongs to the plakin or cytolinker family (1756 aa)
           
  0.560
PEX13
Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins; Peroxins (403 aa)
       
      0.513
C16orf90
Uncharacterized protein C16orf90; Chromosome 16 open reading frame 90 (182 aa)
           
  0.443
WBSCR27
Methyltransferase-like protein 27; Williams Beuren syndrome chromosome region 27 (245 aa)
           
  0.414
OR10C1
Olfactory receptor 10C1; Odorant receptor; Olfactory receptors, family 10 (312 aa)
           
  0.403
OR14J1
Olfactory receptor 14J1; Odorant receptor; Olfactory receptors, family 14 (321 aa)
           
  0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
Server load: low (12%) [HD]