C12orf29 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANGEL2	C12orf29	ENSP00000355929	ENSP00000349358	Angel homolog 2.	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	0.572
C12orf29	ANGEL2	ENSP00000349358	ENSP00000355929	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	Angel homolog 2.	0.572
C12orf29	C12orf50	ENSP00000349358	ENSP00000298699	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	Uncharacterized protein C12orf50; Chromosome 12 open reading frame 50.	0.694
C12orf29	CLUH	ENSP00000349358	ENSP00000458986	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family.	0.508
C12orf29	FAM91A1	ENSP00000349358	ENSP00000335082	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	Protein FAM91A1; As component of the WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1.	0.537
C12orf29	RASSF9	ENSP00000349358	ENSP00000354884	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells.	0.507
C12orf29	SERBP1	ENSP00000349358	ENSP00000360034	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	Plasminogen activator inhibitor 1 RNA-binding protein; May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation.	0.487
C12orf29	SPX	ENSP00000349358	ENSP00000256969	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	Spexin-1; Plays a role as a central modulator of cardiovascular and renal function and nociception. Plays also a role in energy metabolism and storage. Inhibits adrenocortical cell proliferation with minor stimulation on corticosteroid release (By similarity). [Spexin-2]: Intracerebroventricular administration of the peptide induces a decrease in heart rate, but no change in arterial pressure, and an increase in urine flow rate. Intraventricular administration of the peptide induces antinociceptive activity (By similarity).	0.491
C12orf29	TMTC3	ENSP00000349358	ENSP00000266712	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	Protein O-mannosyl-transferase TMTC3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O- mannosyl-transferase on other proteins such as PDIA3. Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response.	0.509
C12orf29	TSPAN19	ENSP00000349358	ENSP00000433816	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	Putative tetraspanin-19; Tetraspanin 19.	0.560
C12orf29	ZNF644	ENSP00000349358	ENSP00000359469	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	Zinc finger protein 644; May be involved in transcriptional regulation.	0.497
C12orf50	C12orf29	ENSP00000298699	ENSP00000349358	Uncharacterized protein C12orf50; Chromosome 12 open reading frame 50.	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	0.694
C12orf50	RASSF9	ENSP00000298699	ENSP00000354884	Uncharacterized protein C12orf50; Chromosome 12 open reading frame 50.	Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells.	0.538
C12orf50	TMTC3	ENSP00000298699	ENSP00000266712	Uncharacterized protein C12orf50; Chromosome 12 open reading frame 50.	Protein O-mannosyl-transferase TMTC3; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O- mannosyl-transferase on other proteins such as PDIA3. Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response.	0.524
C12orf50	TSPAN19	ENSP00000298699	ENSP00000433816	Uncharacterized protein C12orf50; Chromosome 12 open reading frame 50.	Putative tetraspanin-19; Tetraspanin 19.	0.591
CLUH	C12orf29	ENSP00000458986	ENSP00000349358	Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family.	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	0.508
CLUH	FAM91A1	ENSP00000458986	ENSP00000335082	Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family.	Protein FAM91A1; As component of the WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1.	0.471
FAM91A1	C12orf29	ENSP00000335082	ENSP00000349358	Protein FAM91A1; As component of the WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1.	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	0.537
FAM91A1	CLUH	ENSP00000335082	ENSP00000458986	Protein FAM91A1; As component of the WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1.	Clustered mitochondria protein homolog; mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear- encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis; Belongs to the CLU family.	0.471
RASSF9	C12orf29	ENSP00000354884	ENSP00000349358	Ras association domain-containing protein 9; May play a role in regulating vesicuar trafficking in cells.	Uncharacterized protein C12orf29; Chromosome 12 open reading frame 29.	0.507