node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C20orf27 | CPNE1 | ENSP00000217195 | ENSP00000317257 | UPF0687 protein C20orf27; Chromosome 20 open reading frame 27. | Copine-1; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium- dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium- independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcription [...] | 0.541 |
C20orf27 | JCAD | ENSP00000217195 | ENSP00000364526 | UPF0687 protein C20orf27; Chromosome 20 open reading frame 27. | Junctional protein associated with coronary artery disease; Junctional cadherin 5 associated. | 0.552 |
C20orf27 | PCYT2 | ENSP00000217195 | ENSP00000442050 | UPF0687 protein C20orf27; Chromosome 20 open reading frame 27. | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine. | 0.526 |
C20orf27 | TOR4A | ENSP00000217195 | ENSP00000350102 | UPF0687 protein C20orf27; Chromosome 20 open reading frame 27. | Torsin-4A; Torsin family 4 member A. | 0.522 |
CPNE1 | C20orf27 | ENSP00000317257 | ENSP00000217195 | Copine-1; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium- dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium- independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcription [...] | UPF0687 protein C20orf27; Chromosome 20 open reading frame 27. | 0.541 |
CPNE1 | JCAD | ENSP00000317257 | ENSP00000364526 | Copine-1; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium- dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium- independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcription [...] | Junctional protein associated with coronary artery disease; Junctional cadherin 5 associated. | 0.442 |
CPNE1 | PCYT2 | ENSP00000317257 | ENSP00000442050 | Copine-1; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium- dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium- independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcription [...] | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine. | 0.443 |
CPNE1 | PDLIM2 | ENSP00000317257 | ENSP00000312634 | Copine-1; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium- dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium- independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcription [...] | PDZ and LIM domain protein 2; Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity. | 0.415 |
CPNE1 | TOR4A | ENSP00000317257 | ENSP00000350102 | Copine-1; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium- dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium- independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcription [...] | Torsin-4A; Torsin family 4 member A. | 0.515 |
JCAD | C20orf27 | ENSP00000364526 | ENSP00000217195 | Junctional protein associated with coronary artery disease; Junctional cadherin 5 associated. | UPF0687 protein C20orf27; Chromosome 20 open reading frame 27. | 0.552 |
JCAD | CPNE1 | ENSP00000364526 | ENSP00000317257 | Junctional protein associated with coronary artery disease; Junctional cadherin 5 associated. | Copine-1; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium- dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium- independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcription [...] | 0.442 |
JCAD | PCYT2 | ENSP00000364526 | ENSP00000442050 | Junctional protein associated with coronary artery disease; Junctional cadherin 5 associated. | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine. | 0.437 |
JCAD | PDLIM2 | ENSP00000364526 | ENSP00000312634 | Junctional protein associated with coronary artery disease; Junctional cadherin 5 associated. | PDZ and LIM domain protein 2; Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity. | 0.430 |
JCAD | TOR4A | ENSP00000364526 | ENSP00000350102 | Junctional protein associated with coronary artery disease; Junctional cadherin 5 associated. | Torsin-4A; Torsin family 4 member A. | 0.490 |
PCYT2 | C20orf27 | ENSP00000442050 | ENSP00000217195 | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine. | UPF0687 protein C20orf27; Chromosome 20 open reading frame 27. | 0.526 |
PCYT2 | CPNE1 | ENSP00000442050 | ENSP00000317257 | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine. | Copine-1; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium- dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium- independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcription [...] | 0.443 |
PCYT2 | JCAD | ENSP00000442050 | ENSP00000364526 | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine. | Junctional protein associated with coronary artery disease; Junctional cadherin 5 associated. | 0.437 |
PCYT2 | PDLIM2 | ENSP00000442050 | ENSP00000312634 | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine. | PDZ and LIM domain protein 2; Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity. | 0.421 |
PCYT2 | TOR4A | ENSP00000442050 | ENSP00000350102 | Ethanolamine-phosphate cytidylyltransferase; Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP- ethanolamine. | Torsin-4A; Torsin family 4 member A. | 0.538 |
PDLIM2 | CPNE1 | ENSP00000312634 | ENSP00000317257 | PDZ and LIM domain protein 2; Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity. | Copine-1; Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Involved in the TNF-alpha receptor signaling pathway in a calcium- dependent manner. Exhibits calcium-dependent phospholipid binding properties. Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium- independent manner. May recruit target proteins to the cell membrane in a calcium-dependent manner. May function in membrane trafficking. Involved in TNF-alpha-induced NF-kappa-B transcription [...] | 0.415 |