| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| TRIM28 | ZFP28 | ENSP00000253024 | ENSP00000301318 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 28 homolog; May be involved in transcriptional regulation. May have a role in embryonic development. | 0.606 |
| TRIM28 | ZNF233 | ENSP00000253024 | ENSP00000375820 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 233; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.501 |
| TRIM28 | ZNF285 | ENSP00000253024 | ENSP00000464788 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 285; May be involved in transcriptional regulation. | 0.501 |
| TRIM28 | ZNF415 | ENSP00000253024 | ENSP00000439435 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 415; Involved in transcriptional regulation. Transcriptional activity differed among the various isoforms. All isoforms except isoform 3 seem to suppresses the transcriptional activities of AP-1 and p53/TP53. | 0.501 |
| TRIM28 | ZNF441 | ENSP00000253024 | ENSP00000350576 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 441; May be involved in transcriptional regulation. | 0.934 |
| TRIM28 | ZNF563 | ENSP00000253024 | ENSP00000293725 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 563; May be involved in transcriptional regulation. | 0.717 |
| TRIM28 | ZNF625 | ENSP00000253024 | ENSP00000394380 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 625; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.501 |
| TRIM28 | ZNF660 | ENSP00000253024 | ENSP00000324605 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 660; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.501 |
| TRIM28 | ZNF791 | ENSP00000253024 | ENSP00000342974 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 791; May be involved in transcriptional regulation. | 0.775 |
| ZFP28 | TRIM28 | ENSP00000301318 | ENSP00000253024 | Zinc finger protein 28 homolog; May be involved in transcriptional regulation. May have a role in embryonic development. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.606 |
| ZFP28 | ZNF233 | ENSP00000301318 | ENSP00000375820 | Zinc finger protein 28 homolog; May be involved in transcriptional regulation. May have a role in embryonic development. | Zinc finger protein 233; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.511 |
| ZFP28 | ZNF285 | ENSP00000301318 | ENSP00000464788 | Zinc finger protein 28 homolog; May be involved in transcriptional regulation. May have a role in embryonic development. | Zinc finger protein 285; May be involved in transcriptional regulation. | 0.526 |
| ZFP28 | ZNF415 | ENSP00000301318 | ENSP00000439435 | Zinc finger protein 28 homolog; May be involved in transcriptional regulation. May have a role in embryonic development. | Zinc finger protein 415; Involved in transcriptional regulation. Transcriptional activity differed among the various isoforms. All isoforms except isoform 3 seem to suppresses the transcriptional activities of AP-1 and p53/TP53. | 0.514 |
| ZFP28 | ZNF441 | ENSP00000301318 | ENSP00000350576 | Zinc finger protein 28 homolog; May be involved in transcriptional regulation. May have a role in embryonic development. | Zinc finger protein 441; May be involved in transcriptional regulation. | 0.749 |
| ZFP28 | ZNF563 | ENSP00000301318 | ENSP00000293725 | Zinc finger protein 28 homolog; May be involved in transcriptional regulation. May have a role in embryonic development. | Zinc finger protein 563; May be involved in transcriptional regulation. | 0.597 |
| ZFP28 | ZNF791 | ENSP00000301318 | ENSP00000342974 | Zinc finger protein 28 homolog; May be involved in transcriptional regulation. May have a role in embryonic development. | Zinc finger protein 791; May be involved in transcriptional regulation. | 0.589 |
| ZFP28 | ZNF844 | ENSP00000301318 | ENSP00000392024 | Zinc finger protein 28 homolog; May be involved in transcriptional regulation. May have a role in embryonic development. | Zinc finger protein 844; May be involved in transcriptional regulation. | 0.865 |
| ZNF233 | TRIM28 | ENSP00000375820 | ENSP00000253024 | Zinc finger protein 233; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.501 |
| ZNF233 | ZFP28 | ENSP00000375820 | ENSP00000301318 | Zinc finger protein 233; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 28 homolog; May be involved in transcriptional regulation. May have a role in embryonic development. | 0.511 |
| ZNF233 | ZNF285 | ENSP00000375820 | ENSP00000464788 | Zinc finger protein 233; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 285; May be involved in transcriptional regulation. | 0.940 |