C8orf86 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C12orf45	C20orf194	ENSP00000447057	ENSP00000252032	Uncharacterized protein C12orf45; Chromosome 12 open reading frame 45.	Uncharacterized protein C20orf194; May act as an effector for ARL3.	0.441
C12orf45	C6orf201	ENSP00000447057	ENSP00000420610	Uncharacterized protein C12orf45; Chromosome 12 open reading frame 45.	Uncharacterized protein C6orf201; Chromosome 6 open reading frame 201.	0.500
C12orf45	C8orf86	ENSP00000447057	ENSP00000350856	Uncharacterized protein C12orf45; Chromosome 12 open reading frame 45.	Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.	0.426
C12orf45	CPHXL	ENSP00000447057	ENSP00000491599	Uncharacterized protein C12orf45; Chromosome 12 open reading frame 45.	Cytoplasmic polyadenylated homeobox like.	0.440
C20orf194	C12orf45	ENSP00000252032	ENSP00000447057	Uncharacterized protein C20orf194; May act as an effector for ARL3.	Uncharacterized protein C12orf45; Chromosome 12 open reading frame 45.	0.441
C20orf194	C6orf201	ENSP00000252032	ENSP00000420610	Uncharacterized protein C20orf194; May act as an effector for ARL3.	Uncharacterized protein C6orf201; Chromosome 6 open reading frame 201.	0.520
C20orf194	C8orf86	ENSP00000252032	ENSP00000350856	Uncharacterized protein C20orf194; May act as an effector for ARL3.	Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.	0.429
C20orf194	CPHXL	ENSP00000252032	ENSP00000491599	Uncharacterized protein C20orf194; May act as an effector for ARL3.	Cytoplasmic polyadenylated homeobox like.	0.441
C3orf36	C8orf86	ENSP00000386219	ENSP00000350856	Uncharacterized protein C3orf36.	Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.	0.491
C3orf36	CCDC140	ENSP00000386219	ENSP00000295226	Uncharacterized protein C3orf36.	Coiled-coil domain-containing protein 140; CCDC140 long non-coding RNA.	0.522
C6orf201	C12orf45	ENSP00000420610	ENSP00000447057	Uncharacterized protein C6orf201; Chromosome 6 open reading frame 201.	Uncharacterized protein C12orf45; Chromosome 12 open reading frame 45.	0.500
C6orf201	C20orf194	ENSP00000420610	ENSP00000252032	Uncharacterized protein C6orf201; Chromosome 6 open reading frame 201.	Uncharacterized protein C20orf194; May act as an effector for ARL3.	0.520
C6orf201	C8orf86	ENSP00000420610	ENSP00000350856	Uncharacterized protein C6orf201; Chromosome 6 open reading frame 201.	Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.	0.499
C6orf201	CPHXL	ENSP00000420610	ENSP00000491599	Uncharacterized protein C6orf201; Chromosome 6 open reading frame 201.	Cytoplasmic polyadenylated homeobox like.	0.515
C6orf201	RNF123	ENSP00000420610	ENSP00000328287	Uncharacterized protein C6orf201; Chromosome 6 open reading frame 201.	E3 ubiquitin-protein ligase RNF123; Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Promotes the ubiquitination and proteasome- mediated degradation of CDKN1B which is the cyclin-dependent kinase inhibitor at the G0-G1 transition of the cell cycle. Functions also as an inhibitor of innate antiviral signaling mediated by DDX58 and IFIH1 independently of its E3 ligase activity. Interacts with the N-terminal CARD domains of DDX58 and IFIH1 and competes with the downstream adapter MAVS.	0.457
C8orf86	C12orf45	ENSP00000350856	ENSP00000447057	Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.	Uncharacterized protein C12orf45; Chromosome 12 open reading frame 45.	0.426
C8orf86	C20orf194	ENSP00000350856	ENSP00000252032	Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.	Uncharacterized protein C20orf194; May act as an effector for ARL3.	0.429
C8orf86	C3orf36	ENSP00000350856	ENSP00000386219	Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.	Uncharacterized protein C3orf36.	0.491
C8orf86	C6orf201	ENSP00000350856	ENSP00000420610	Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.	Uncharacterized protein C6orf201; Chromosome 6 open reading frame 201.	0.499
C8orf86	CCDC140	ENSP00000350856	ENSP00000295226	Uncharacterized protein C8orf86; Chromosome 8 open reading frame 86.	Coiled-coil domain-containing protein 140; CCDC140 long non-coding RNA.	0.430