node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL1A1 | COL1A2 | ENSP00000225964 | ENSP00000297268 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | 0.999 |
COL1A1 | COL26A1 | ENSP00000225964 | ENSP00000318234 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Collagen type XXVI alpha 1 chain. | 0.628 |
COL1A1 | COL3A1 | ENSP00000225964 | ENSP00000304408 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. | 0.999 |
COL1A1 | COL4A2 | ENSP00000225964 | ENSP00000353654 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Collagen alpha-2(IV) chain; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. | 0.698 |
COL1A1 | COL5A2 | ENSP00000225964 | ENSP00000364000 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Collagen alpha-2(V) chain; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices (By similarity). | 0.995 |
COL1A1 | CRTAP | ENSP00000225964 | ENSP00000323696 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Cartilage-associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues; Belongs to the leprecan family. | 0.971 |
COL1A1 | FKBP10 | ENSP00000225964 | ENSP00000317232 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis. | 0.804 |
COL1A1 | MMP8 | ENSP00000225964 | ENSP00000236826 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Neutrophil collagenase; Can degrade fibrillar type I, II, and III collagens; Belongs to the peptidase M10A family. | 0.428 |
COL1A1 | P3H1 | ENSP00000225964 | ENSP00000236040 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Prolyl 3-hydroxylase 1; Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post- translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts. | 0.945 |
COL1A1 | SERPINH1 | ENSP00000225964 | ENSP00000434412 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | Serpin H1; Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. | 0.921 |
COL1A2 | COL1A1 | ENSP00000297268 | ENSP00000225964 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | 0.999 |
COL1A2 | COL26A1 | ENSP00000297268 | ENSP00000318234 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Collagen type XXVI alpha 1 chain. | 0.675 |
COL1A2 | COL3A1 | ENSP00000297268 | ENSP00000304408 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. | 0.999 |
COL1A2 | COL4A2 | ENSP00000297268 | ENSP00000353654 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Collagen alpha-2(IV) chain; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. | 0.786 |
COL1A2 | COL5A2 | ENSP00000297268 | ENSP00000364000 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Collagen alpha-2(V) chain; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices (By similarity). | 0.998 |
COL1A2 | CRTAP | ENSP00000297268 | ENSP00000323696 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Cartilage-associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues; Belongs to the leprecan family. | 0.964 |
COL1A2 | FKBP10 | ENSP00000297268 | ENSP00000317232 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis. | 0.871 |
COL1A2 | P3H1 | ENSP00000297268 | ENSP00000236040 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Prolyl 3-hydroxylase 1; Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post- translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts. | 0.945 |
COL1A2 | SERPINH1 | ENSP00000297268 | ENSP00000434412 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Serpin H1; Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. | 0.879 |
COL26A1 | COL1A1 | ENSP00000318234 | ENSP00000225964 | Collagen type XXVI alpha 1 chain. | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). | 0.628 |