FHAD1 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALOX12B	FHAD1	ENSP00000497784	ENSP00000351770	Arachidonate 12-lipoxygenase, 12R-type; Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipid hydroperoxides that can be further reduced to the corresponding hydroxy species. In the skin, acts upstream of ALOXE3 on the lineolate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid enve [...]	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	0.566
CFAP52	CFAP57	ENSP00000339449	ENSP00000479773	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.	Cilia and flagella associated protein 57.	0.788
CFAP52	FHAD1	ENSP00000339449	ENSP00000351770	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	0.495
CFAP52	HYDIN	ENSP00000339449	ENSP00000377197	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.	Hydrocephalus-inducing protein homolog; Required for ciliary motility.	0.458
CFAP57	CFAP52	ENSP00000479773	ENSP00000339449	Cilia and flagella associated protein 57.	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.	0.788
CFAP57	FHAD1	ENSP00000479773	ENSP00000351770	Cilia and flagella associated protein 57.	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	0.461
CFAP57	HYDIN	ENSP00000479773	ENSP00000377197	Cilia and flagella associated protein 57.	Hydrocephalus-inducing protein homolog; Required for ciliary motility.	0.504
FHAD1	ALOX12B	ENSP00000351770	ENSP00000497784	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	Arachidonate 12-lipoxygenase, 12R-type; Catalyzes the regio and stereo-specific incorporation of a single molecule of dioxygen into free and esterified polyunsaturated fatty acids generating lipid hydroperoxides that can be further reduced to the corresponding hydroxy species. In the skin, acts upstream of ALOXE3 on the lineolate moiety of esterified omega-hydroxyacyl-sphingosine (EOS) ceramides to produce an epoxy-ketone derivative, a crucial step in the conjugation of omega-hydroxyceramide to membrane proteins. Therefore plays a crucial role in the synthesis of corneocytes lipid enve [...]	0.566
FHAD1	CFAP52	ENSP00000351770	ENSP00000339449	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.	0.495
FHAD1	CFAP57	ENSP00000351770	ENSP00000479773	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	Cilia and flagella associated protein 57.	0.461
FHAD1	HYDIN	ENSP00000351770	ENSP00000377197	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	Hydrocephalus-inducing protein homolog; Required for ciliary motility.	0.495
FHAD1	KIF14	ENSP00000351770	ENSP00000356319	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	Kinesin-like protein KIF14; Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis. During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively. Regulates cell growth through regulation of cell cycle progression and cytokinesis. During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic [...]	0.457
FHAD1	KLHL8	ENSP00000351770	ENSP00000273963	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	Kelch-like protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for The BCR(KLHL8) ubiquitin ligase complex mediates ubiquitination and degradation of RAPSN.	0.570
FHAD1	PI15	ENSP00000351770	ENSP00000260113	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	Peptidase inhibitor 15; Serine protease inhibitor which displays weak inhibitory activity against trypsin. May play a role in facial patterning during embryonic development (By similarity). Belongs to the CRISP family.	0.440
FHAD1	SEL1L3	ENSP00000351770	ENSP00000382767	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	Protein sel-1 homolog 3; SEL1L family member 3.	0.468
FHAD1	SUSD4	ENSP00000351770	ENSP00000344219	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	Sushi domain-containing protein 4; Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.	0.469
FHAD1	ZNF407	ENSP00000351770	ENSP00000299687	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	Zinc finger protein 407; May be involved in transcriptional regulation.	0.472
HYDIN	CFAP52	ENSP00000377197	ENSP00000339449	Hydrocephalus-inducing protein homolog; Required for ciliary motility.	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.	0.458
HYDIN	CFAP57	ENSP00000377197	ENSP00000479773	Hydrocephalus-inducing protein homolog; Required for ciliary motility.	Cilia and flagella associated protein 57.	0.504
HYDIN	FHAD1	ENSP00000377197	ENSP00000351770	Hydrocephalus-inducing protein homolog; Required for ciliary motility.	Forkhead-associated domain-containing protein 1; Forkhead associated phosphopeptide binding domain 1.	0.495