node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD30A | ANKRD30B | ENSP00000354432 | ENSP00000499676 | Ankyrin repeat domain 30A. | Ankyrin repeat domain 30B. | 0.492 |
ANKRD30A | ANKRD39 | ENSP00000354432 | ENSP00000377170 | Ankyrin repeat domain 30A. | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | 0.475 |
ANKRD30A | ASB15 | ENSP00000354432 | ENSP00000397655 | Ankyrin repeat domain 30A. | Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.489 |
ANKRD30A | CDKN2C | ENSP00000354432 | ENSP00000262662 | Ankyrin repeat domain 30A. | Cyclin-dependent kinase 4 inhibitor C; Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB; Belongs to the CDKN2 cyclin-dependent kinase inhibitor family. | 0.453 |
ANKRD30B | ANKRD30A | ENSP00000499676 | ENSP00000354432 | Ankyrin repeat domain 30B. | Ankyrin repeat domain 30A. | 0.492 |
ANKRD30B | ANKRD39 | ENSP00000499676 | ENSP00000377170 | Ankyrin repeat domain 30B. | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | 0.507 |
ANKRD30B | ASB12 | ENSP00000499676 | ENSP00000355195 | Ankyrin repeat domain 30B. | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.437 |
ANKRD30B | ASB15 | ENSP00000499676 | ENSP00000397655 | Ankyrin repeat domain 30B. | Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.511 |
ANKRD30B | BUD23 | ENSP00000499676 | ENSP00000401191 | Ankyrin repeat domain 30B. | Probable 18S rRNA (guanine-N(7))-methyltransferase; S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(7) position of a guanine in 18S rRNA. Requires the methyltransferase adapter protein TRM112 for full rRNA methyltransferase activity. Involved in the pre-rRNA processing steps leading to small-subunit rRNA production independently of its RNA-modifying catalytic activity. Important for biogenesis end export of the 40S ribosomal subunit independent on its methyltransferase activity. Locus-specific steroid receptor coactivator. Potentiates transactivat [...] | 0.427 |
ANKRD30B | CDKN2C | ENSP00000499676 | ENSP00000262662 | Ankyrin repeat domain 30B. | Cyclin-dependent kinase 4 inhibitor C; Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB; Belongs to the CDKN2 cyclin-dependent kinase inhibitor family. | 0.487 |
ANKRD30B | GABPB2 | ENSP00000499676 | ENSP00000357914 | Ankyrin repeat domain 30B. | GA-binding protein subunit beta-2; May function as transcription factor capable of interacting with purine rich repeats (GA repeats). | 0.435 |
ANKRD30B | MTPN | ENSP00000499676 | ENSP00000376800 | Ankyrin repeat domain 30B. | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Belongs to the myotrophin family. | 0.444 |
ANKRD30B | NFKBIA | ENSP00000499676 | ENSP00000216797 | Ankyrin repeat domain 30B. | NF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. | 0.505 |
ANKRD39 | ANKRD30A | ENSP00000377170 | ENSP00000354432 | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | Ankyrin repeat domain 30A. | 0.475 |
ANKRD39 | ANKRD30B | ENSP00000377170 | ENSP00000499676 | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | Ankyrin repeat domain 30B. | 0.507 |
ANKRD39 | ASB12 | ENSP00000377170 | ENSP00000355195 | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.459 |
ANKRD39 | NFKBIA | ENSP00000377170 | ENSP00000216797 | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | NF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. | 0.510 |
ASB12 | ANKRD30B | ENSP00000355195 | ENSP00000499676 | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Ankyrin repeat domain 30B. | 0.437 |
ASB12 | ANKRD39 | ENSP00000355195 | ENSP00000377170 | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Ankyrin repeat domain 39; Belongs to the ANKRD39 family. | 0.459 |
ASB12 | CDKN2C | ENSP00000355195 | ENSP00000262662 | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Cyclin-dependent kinase 4 inhibitor C; Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB; Belongs to the CDKN2 cyclin-dependent kinase inhibitor family. | 0.501 |