STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLFNL1Schlafen-like protein 1; Schlafen like 1. (407 aa)    
Predicted Functional Partners:
STPG3
Protein STPG3; Sperm-tail PG-rich repeat containing 3.
   
  
 0.696
TEX36
Testis-expressed protein 36; Testis expressed 36.
   
  
 0.682
SMKR1
Small lysine rich protein 1.
   
 
 0.644
GLT6D1
Glycosyltransferase 6 domain containing 1; Belongs to the glycosyltransferase 6 family.
   
  
 0.633
FAM187B
Protein FAM187B; Family with sequence similarity 187 member B.
   
  
 0.610
EVPLL
Envoplakin-like protein; Envoplakin like; Belongs to the plakin or cytolinker family.
      
 0.571
SPPL2C
Signal peptide peptidase-like 2C; Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane.
   
  
 0.556
ZNF587B
Zinc finger protein 587B; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
   
 
 0.531
PRSS58
Serine protease 58; Belongs to the peptidase S1 family.
   
 
 0.491
EPRS1
Bifunctional glutamate/proline--tRNA ligase; Multifunctional protein which is primarily part of the aminoacyl-tRNA synthetase multienzyme complex, also know as multisynthetase complex, that catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. The phosphorylation of EPRS1, induced by interferon-gamma, dissociates the protein from the aminoacyl-tRNA synthetase multienzyme complex and recruits it [...]
  
 
 0.487
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.