STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD53Ankyrin repeat domain-containing protein 53; Required for normal progression through mitosis. Involved in chromosome alignment and cytokinesis via regulation of microtubules polymerization. (530 aa)    
Predicted Functional Partners:
TDRD10
Tudor domain containing 10.
   
  
 0.578
ZNF154
Zinc finger protein 154; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
    
 
 0.566
EFCAB1
EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1.
   
 
 0.461
PLEKHS1
Pleckstrin homology domain containing S1.
   
  
 0.454
TAF11
Transcription initiation factor TFIID subunit 11; Core TAFII present in both of the previously described TFIID species which either lack or contain TAFII30 (TFIID alpha and TFIID beta respectively); Belongs to the TAF11 family.
      
 0.433
ZNF177
Zinc finger protein 177; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
    
 
 0.426
PRAC2
PRAC2 small nuclear protein.
      
 0.418
LOC100288966
POTE ankyrin domain family member D-like.
  
 
 
 0.417
POTED
POTE ankyrin domain family member D; Belongs to the POTE family.
  
 
 
 0.416
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.