FAM110A protein (human) - STRING interaction network

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Score

FAM110A

Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family. (295 aa)

Predicted Functional Partners:

CSPP1

0.947

TM2D2

0.510

ZMAT4

0.489

KCTD3

0.479

ZDHHC18

0.479

IRS4

0.472

PLEKHA2

0.470

GPR101

0.460

GPANK1

0.451

SMIM13

0.446

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSPP1	FAM110A	ENSP00000262210	ENSP00000354163	Centrosome and spindle pole-associated protein 1; May play a role in cell-cycle-dependent microtubule organization.	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	0.947
FAM110A	CSPP1	ENSP00000354163	ENSP00000262210	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	Centrosome and spindle pole-associated protein 1; May play a role in cell-cycle-dependent microtubule organization.	0.947
FAM110A	GPANK1	ENSP00000354163	ENSP00000365071	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	G-patch domain and ankyrin repeats 1.	0.451
FAM110A	GPR101	ENSP00000354163	ENSP00000498972	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	Probable G-protein coupled receptor 101; Orphan receptor.	0.460
FAM110A	IRS4	ENSP00000354163	ENSP00000361202	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	Insulin receptor substrate 4; Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex network of intracellular signaling molecules containing SH2 domains. Involved in the IGF1R mitogenic signaling pathway. Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis. Interaction with GRB2 enhances insulin- stimulated mitogen-activated protein kinase activity. May be involved in nonreceptor tyrosine kin [...]	0.472
FAM110A	KCTD3	ENSP00000354163	ENSP00000259154	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	BTB/POZ domain-containing protein KCTD3; Accessory subunit of potassium/sodium hyperpolarization- activated cyclic nucleotide-gated channel 3 (HCN3) upregulating its cell-surface expression and current density without affecting its voltage dependence and kinetics; Belongs to the KCTD3 family.	0.479
FAM110A	PLEKHA2	ENSP00000354163	ENSP00000482228	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity).	0.470
FAM110A	SMIM13	ENSP00000354163	ENSP00000451866	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	Small integral membrane protein 13.	0.446
FAM110A	TM2D2	ENSP00000354163	ENSP00000416050	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	TM2 domain containing 2.	0.510
FAM110A	ZDHHC18	ENSP00000354163	ENSP00000363257	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	Palmitoyltransferase ZDHHC18; Has palmitoyltransferase activity towards HRAS and LCK.	0.479
FAM110A	ZMAT4	ENSP00000354163	ENSP00000297737	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	Zinc finger matrin-type 4.	0.489
GPANK1	FAM110A	ENSP00000365071	ENSP00000354163	G-patch domain and ankyrin repeats 1.	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	0.451
GPR101	FAM110A	ENSP00000498972	ENSP00000354163	Probable G-protein coupled receptor 101; Orphan receptor.	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	0.460
GPR101	IRS4	ENSP00000498972	ENSP00000361202	Probable G-protein coupled receptor 101; Orphan receptor.	Insulin receptor substrate 4; Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex network of intracellular signaling molecules containing SH2 domains. Involved in the IGF1R mitogenic signaling pathway. Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis. Interaction with GRB2 enhances insulin- stimulated mitogen-activated protein kinase activity. May be involved in nonreceptor tyrosine kin [...]	0.544
IRS4	FAM110A	ENSP00000361202	ENSP00000354163	Insulin receptor substrate 4; Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex network of intracellular signaling molecules containing SH2 domains. Involved in the IGF1R mitogenic signaling pathway. Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis. Interaction with GRB2 enhances insulin- stimulated mitogen-activated protein kinase activity. May be involved in nonreceptor tyrosine kin [...]	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	0.472
IRS4	GPR101	ENSP00000361202	ENSP00000498972	Insulin receptor substrate 4; Acts as an interface between multiple growth factor receptors possessing tyrosine kinase activity, such as insulin receptor, IGF1R and FGFR1, and a complex network of intracellular signaling molecules containing SH2 domains. Involved in the IGF1R mitogenic signaling pathway. Promotes the AKT1 signaling pathway and BAD phosphorylation during insulin stimulation without activation of RPS6KB1 or the inhibition of apoptosis. Interaction with GRB2 enhances insulin- stimulated mitogen-activated protein kinase activity. May be involved in nonreceptor tyrosine kin [...]	Probable G-protein coupled receptor 101; Orphan receptor.	0.544
KCTD3	FAM110A	ENSP00000259154	ENSP00000354163	BTB/POZ domain-containing protein KCTD3; Accessory subunit of potassium/sodium hyperpolarization- activated cyclic nucleotide-gated channel 3 (HCN3) upregulating its cell-surface expression and current density without affecting its voltage dependence and kinetics; Belongs to the KCTD3 family.	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	0.479
PLEKHA2	FAM110A	ENSP00000482228	ENSP00000354163	Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity).	Protein FAM110A; Family with sequence similarity 110 member A; Belongs to the FAM110 family.	0.470
PLEKHA2	TM2D2	ENSP00000482228	ENSP00000416050	Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity).	TM2 domain containing 2.	0.620
PLEKHA2	ZMAT4	ENSP00000482228	ENSP00000297737	Pleckstrin homology domain-containing family A member 2; Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane (By similarity).	Zinc finger matrin-type 4.	0.438