node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCNDBP1 | ZNF627 | ENSP00000300213 | ENSP00000354414 | Cyclin-D1-binding protein 1; May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. | Zinc finger protein 627; May be involved in transcriptional regulation. | 0.585 |
NBPF14 | ZNF627 | ENSP00000479693 | ENSP00000354414 | Neuroblastoma breakpoint family member 14; NBPF member 14. | Zinc finger protein 627; May be involved in transcriptional regulation. | 0.405 |
OR13G1 | TAS2R50 | ENSP00000493110 | ENSP00000424040 | Olfactory receptor 13G1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Taste receptor type 2 member 50; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity); Belongs to the G-protein coupled receptor T2R family. | 0.979 |
OR13G1 | ZNF627 | ENSP00000493110 | ENSP00000354414 | Olfactory receptor 13G1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Zinc finger protein 627; May be involved in transcriptional regulation. | 0.620 |
TAS2R50 | OR13G1 | ENSP00000424040 | ENSP00000493110 | Taste receptor type 2 member 50; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity); Belongs to the G-protein coupled receptor T2R family. | Olfactory receptor 13G1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.979 |
TAS2R50 | ZNF627 | ENSP00000424040 | ENSP00000354414 | Taste receptor type 2 member 50; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity); Belongs to the G-protein coupled receptor T2R family. | Zinc finger protein 627; May be involved in transcriptional regulation. | 0.578 |
TMEM167B | ZNF627 | ENSP00000342148 | ENSP00000354414 | Protein kish-B; Involved in the early part of the secretory pathway. Belongs to the KISH family. | Zinc finger protein 627; May be involved in transcriptional regulation. | 0.433 |
TRIM28 | ZNF627 | ENSP00000253024 | ENSP00000354414 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 627; May be involved in transcriptional regulation. | 0.618 |
ZNF627 | CCNDBP1 | ENSP00000354414 | ENSP00000300213 | Zinc finger protein 627; May be involved in transcriptional regulation. | Cyclin-D1-binding protein 1; May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription. | 0.585 |
ZNF627 | NBPF14 | ENSP00000354414 | ENSP00000479693 | Zinc finger protein 627; May be involved in transcriptional regulation. | Neuroblastoma breakpoint family member 14; NBPF member 14. | 0.405 |
ZNF627 | OR13G1 | ENSP00000354414 | ENSP00000493110 | Zinc finger protein 627; May be involved in transcriptional regulation. | Olfactory receptor 13G1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.620 |
ZNF627 | TAS2R50 | ENSP00000354414 | ENSP00000424040 | Zinc finger protein 627; May be involved in transcriptional regulation. | Taste receptor type 2 member 50; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity); Belongs to the G-protein coupled receptor T2R family. | 0.578 |
ZNF627 | TMEM167B | ENSP00000354414 | ENSP00000342148 | Zinc finger protein 627; May be involved in transcriptional regulation. | Protein kish-B; Involved in the early part of the secretory pathway. Belongs to the KISH family. | 0.433 |
ZNF627 | TRIM28 | ENSP00000354414 | ENSP00000253024 | Zinc finger protein 627; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.618 |
ZNF627 | ZZZ3 | ENSP00000354414 | ENSP00000359837 | Zinc finger protein 627; May be involved in transcriptional regulation. | ZZ-type zinc finger-containing protein 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. | 0.401 |
ZZZ3 | ZNF627 | ENSP00000359837 | ENSP00000354414 | ZZ-type zinc finger-containing protein 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. | Zinc finger protein 627; May be involved in transcriptional regulation. | 0.401 |