Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SFT2D1Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. (159 aa)    
Predicted Functional Partners:
PRR18
Proline-rich protein 18; Proline rich 18.
      
 0.621
YKT6
Synaptobrevin homolog YKT6; Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.
    
 
 0.581
GOLT1A
Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex; Belongs to the GOT1 family.
   
 
 0.548
C6orf118
Uncharacterized protein C6orf118; Chromosome 6 open reading frame 118.
      
 0.535
STX16
Syntaxin-16; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.
    
 
 0.519
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family.
    
   0.508
CTDNEP1
CTD nuclear envelope phosphatase 1; Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and [...]
      
 0.475
MAL2
Protein MAL2; Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway.
   
  
 0.442
SFT2D3
Vesicle transport protein SFT2C; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.
      
 0.441
GOLT1B
Vesicle transport protein GOT1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
   
 
 0.427
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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