Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity.

Protein FAM178B; Family with sequence similarity 178 member B.

Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Protein FAM178B; Family with sequence similarity 178 member B.

Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity.

Protein FAM178B; Family with sequence similarity 178 member B.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

G-protein coupled receptor 183; G-protein coupled receptor expressed in lymphocytes that acts as a chemotactic receptor for B-cells, T-cells, splenic dendritic cells, monocytes/macrophages and astrocytes (By similarity). Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols. Mediates cell positioning and movement of a number of cells by binding the 7-alpha,25-OHC ligand that forms a chemotactic gradient (By similarity). Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses (By similarity). G [...]

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

5-hydroxytryptamine receptor 2C; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,- dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathway [...]

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Inositol 1,4,5-trisphosphate receptor type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Protein FAM178B; Family with sequence similarity 178 member B.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

G-protein coupled receptor 183; G-protein coupled receptor expressed in lymphocytes that acts as a chemotactic receptor for B-cells, T-cells, splenic dendritic cells, monocytes/macrophages and astrocytes (By similarity). Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols. Mediates cell positioning and movement of a number of cells by binding the 7-alpha,25-OHC ligand that forms a chemotactic gradient (By similarity). Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses (By similarity). G [...]

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

5-hydroxytryptamine receptor 2C; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,- dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathway [...]

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Inositol 1,4,5-trisphosphate receptor type 1; Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5- trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

RNA-binding protein MEX3A; RNA binding protein, may be involved in post-transcriptional regulatory mechanisms.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Small glutamine-rich tetratricopeptide repeat-containing protein alpha; Co-chaperone that binds misfolded and hydrophobic patches- containing client proteins in the cytosol. Mediates their targeting to the endoplasmic reticulum but also regulates their sorting to the proteasome when targeting fails. Functions in tail- anchored/type II transmembrane proteins membrane insertion constituting with ASNA1 and the BAG6 complex a targeting module. Functions upstream of the BAG6 complex and ASNA1, binding more rapidly the transmembrane domain of newly synthesized proteins. It is also involved i [...]

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Transmembrane protein 102; Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Thioredoxin related transmembrane protein 4.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

WD repeat-containing protein 54; When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation.

RNA-binding protein MEX3A; RNA binding protein, may be involved in post-transcriptional regulatory mechanisms.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Small glutamine-rich tetratricopeptide repeat-containing protein alpha; Co-chaperone that binds misfolded and hydrophobic patches- containing client proteins in the cytosol. Mediates their targeting to the endoplasmic reticulum but also regulates their sorting to the proteasome when targeting fails. Functions in tail- anchored/type II transmembrane proteins membrane insertion constituting with ASNA1 and the BAG6 complex a targeting module. Functions upstream of the BAG6 complex and ASNA1, binding more rapidly the transmembrane domain of newly synthesized proteins. It is also involved i [...]

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.

Transmembrane protein 102; Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway.

Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIP like 1.