LRRC10 protein (human) - STRING interaction network

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Score

LRRC10

Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function. (277 aa)

Predicted Functional Partners:

LRRC26

0.699

CCT2

0.622

BEST3

0.562

NYX

0.554

LRG1

0.536

PRELP

0.527

KERA

0.525

SLMAP

0.522

LUM

0.520

OMD

0.518

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BEST3	CCT2	ENSP00000332413	ENSP00000299300	Bestrophin-3; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable).	0.538
BEST3	LRRC10	ENSP00000332413	ENSP00000355166	Bestrophin-3; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	0.562
CCT2	BEST3	ENSP00000299300	ENSP00000332413	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable).	Bestrophin-3; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	0.538
CCT2	LRRC10	ENSP00000299300	ENSP00000355166	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable).	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	0.622
KERA	LRRC10	ENSP00000266719	ENSP00000355166	Keratocan; May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	0.525
KERA	LUM	ENSP00000266719	ENSP00000266718	Keratocan; May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.	Lumican; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.	0.806
KERA	NYX	ENSP00000266719	ENSP00000340328	Keratocan; May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.	Nyctalopin.	0.492
KERA	OMD	ENSP00000266719	ENSP00000364700	Keratocan; May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.	Osteomodulin; May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the alpha(V)beta(3)-integrin (By similarity).	0.657
KERA	PRELP	ENSP00000266719	ENSP00000343924	Keratocan; May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.	Prolargin; May anchor basement membranes to the underlying connective tissue.	0.539
LRG1	LRRC10	ENSP00000302621	ENSP00000355166	Leucine rich alpha-2-glycoprotein 1.	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	0.536
LRRC10	BEST3	ENSP00000355166	ENSP00000332413	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Bestrophin-3; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.	0.562
LRRC10	CCT2	ENSP00000355166	ENSP00000299300	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	T-complex protein 1 subunit beta; Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin (Probable).	0.622
LRRC10	KERA	ENSP00000355166	ENSP00000266719	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Keratocan; May be important in developing and maintaining corneal transparency and for the structure of the stromal matrix.	0.525
LRRC10	LRG1	ENSP00000355166	ENSP00000302621	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Leucine rich alpha-2-glycoprotein 1.	0.536
LRRC10	LRRC26	ENSP00000355166	ENSP00000360597	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Leucine-rich repeat-containing protein 26; Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Required for the conversion of BK alpha channels from a high-voltage to a low-voltage activated channel type in non-excitable cells. These are characterized by negative membrane voltages and constant low levels of calcium.	0.699
LRRC10	LUM	ENSP00000355166	ENSP00000266718	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Lumican; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.	0.520
LRRC10	NYX	ENSP00000355166	ENSP00000340328	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Nyctalopin.	0.554
LRRC10	OMD	ENSP00000355166	ENSP00000364700	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Osteomodulin; May be implicated in biomineralization processes. Has a function in binding of osteoblasts via the alpha(V)beta(3)-integrin (By similarity).	0.518
LRRC10	PRELP	ENSP00000355166	ENSP00000343924	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Prolargin; May anchor basement membranes to the underlying connective tissue.	0.527
LRRC10	SLMAP	ENSP00000355166	ENSP00000499241	Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function.	Sarcolemmal membrane-associated protein; May play a role during myoblast fusion; Belongs to the SLMAP family.	0.522