| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHNAK | CCDC185 | ENSP00000367263 | ENSP00000355840 | Neuroblast differentiation-associated protein AHNAK; May be required for neuronal cell differentiation. | Coiled-coil domain containing 185. | 0.449 |
| AHNAK | KIF14 | ENSP00000367263 | ENSP00000356319 | Neuroblast differentiation-associated protein AHNAK; May be required for neuronal cell differentiation. | Kinesin-like protein KIF14; Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis. During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively. Regulates cell growth through regulation of cell cycle progression and cytokinesis. During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic [...] | 0.460 |
| ARL1 | CCDC185 | ENSP00000261636 | ENSP00000355840 | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | Coiled-coil domain containing 185. | 0.577 |
| ARL1 | KIF14 | ENSP00000261636 | ENSP00000356319 | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | Kinesin-like protein KIF14; Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis. During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively. Regulates cell growth through regulation of cell cycle progression and cytokinesis. During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic [...] | 0.457 |
| C4orf33 | CCDC185 | ENSP00000281146 | ENSP00000355840 | UPF0462 protein C4orf33; Chromosome 4 open reading frame 33. | Coiled-coil domain containing 185. | 0.419 |
| C5orf47 | CCDC185 | ENSP00000340887 | ENSP00000355840 | Uncharacterized protein C5orf47; Chromosome 5 open reading frame 47. | Coiled-coil domain containing 185. | 0.531 |
| CATSPER3 | CCDC185 | ENSP00000282611 | ENSP00000355840 | Cation channel sperm-associated protein 3; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. | Coiled-coil domain containing 185. | 0.528 |
| CCDC185 | AHNAK | ENSP00000355840 | ENSP00000367263 | Coiled-coil domain containing 185. | Neuroblast differentiation-associated protein AHNAK; May be required for neuronal cell differentiation. | 0.449 |
| CCDC185 | ARL1 | ENSP00000355840 | ENSP00000261636 | Coiled-coil domain containing 185. | ADP-ribosylation factor-like protein 1; GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. | 0.577 |
| CCDC185 | C4orf33 | ENSP00000355840 | ENSP00000281146 | Coiled-coil domain containing 185. | UPF0462 protein C4orf33; Chromosome 4 open reading frame 33. | 0.419 |
| CCDC185 | C5orf47 | ENSP00000355840 | ENSP00000340887 | Coiled-coil domain containing 185. | Uncharacterized protein C5orf47; Chromosome 5 open reading frame 47. | 0.531 |
| CCDC185 | CATSPER3 | ENSP00000355840 | ENSP00000282611 | Coiled-coil domain containing 185. | Cation channel sperm-associated protein 3; Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. | 0.528 |
| CCDC185 | EPRS1 | ENSP00000355840 | ENSP00000355890 | Coiled-coil domain containing 185. | Bifunctional glutamate/proline--tRNA ligase; Multifunctional protein which is primarily part of the aminoacyl-tRNA synthetase multienzyme complex, also know as multisynthetase complex, that catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. The phosphorylation of EPRS1, induced by interferon-gamma, dissociates the protein from the aminoacyl-tRNA synthetase multienzyme complex and recruits it [...] | 0.479 |
| CCDC185 | KIF14 | ENSP00000355840 | ENSP00000356319 | Coiled-coil domain containing 185. | Kinesin-like protein KIF14; Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis. During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively. Regulates cell growth through regulation of cell cycle progression and cytokinesis. During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic [...] | 0.457 |
| CCDC185 | KXD1 | ENSP00000355840 | ENSP00000472836 | Coiled-coil domain containing 185. | KxDL motif-containing protein 1; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. May be involved in the biogenesis of lysosome- related organelles such as melanosomes (By similarity). Belongs to the KXD1 family. | 0.793 |
| CCDC185 | PLIN1 | ENSP00000355840 | ENSP00000300055 | Coiled-coil domain containing 185. | Perilipin-1; Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels. Belongs to the perilipin family. | 0.449 |
| CCDC185 | ZBED4 | ENSP00000355840 | ENSP00000216268 | Coiled-coil domain containing 185. | Zinc finger BED-type containing 4. | 0.449 |
| EPRS1 | CCDC185 | ENSP00000355890 | ENSP00000355840 | Bifunctional glutamate/proline--tRNA ligase; Multifunctional protein which is primarily part of the aminoacyl-tRNA synthetase multienzyme complex, also know as multisynthetase complex, that catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. The phosphorylation of EPRS1, induced by interferon-gamma, dissociates the protein from the aminoacyl-tRNA synthetase multienzyme complex and recruits it [...] | Coiled-coil domain containing 185. | 0.479 |
| EPRS1 | KIF14 | ENSP00000355890 | ENSP00000356319 | Bifunctional glutamate/proline--tRNA ligase; Multifunctional protein which is primarily part of the aminoacyl-tRNA synthetase multienzyme complex, also know as multisynthetase complex, that catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. The phosphorylation of EPRS1, induced by interferon-gamma, dissociates the protein from the aminoacyl-tRNA synthetase multienzyme complex and recruits it [...] | Kinesin-like protein KIF14; Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis. During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively. Regulates cell growth through regulation of cell cycle progression and cytokinesis. During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic [...] | 0.483 |
| KIF14 | AHNAK | ENSP00000356319 | ENSP00000367263 | Kinesin-like protein KIF14; Microtubule motor protein that binds to microtubules with high affinity through each tubulin heterodimer and has an ATPase activity (By similarity). Plays a role in many processes like cell division, cytokinesis and also in cell proliferation and apoptosis. During cytokinesis, targets to central spindle and midbody through its interaction with PRC1 and CIT respectively. Regulates cell growth through regulation of cell cycle progression and cytokinesis. During cell cycle progression acts through SCF-dependent proteasomal ubiquitin-dependent protein catabolic [...] | Neuroblast differentiation-associated protein AHNAK; May be required for neuronal cell differentiation. | 0.460 |
