STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TEDDM1Transmembrane epididymal protein 1 (273 aa)    
Predicted Functional Partners:
SBK2
Serine/threonine-protein kinase SBK2; SH3 domain binding kinase family member 2
      
 0.758
ODF3L1
Outer dense fiber of sperm tails 3 like 1; Belongs to the ODF3 family
      
 0.609
LY6G5B
Lymphocyte antigen 6 family member G5B; LY6/PLAUR domain containing
      
 0.554
WFDC10A
WAP four-disulfide core domain containing
      
 0.525
CRISP1
Cysteine-rich secretory protein 1; May have a role in sperm-egg fusion and maturation; Belongs to the CRISP family
      
 0.515
DEFB125
Beta-defensin 125; Has antibacterial activity; Defensins, beta
      
 0.510
DEFB30
Defensin, beta 130; Antimicrobial host-defense peptide. Has an antiplasmodial activity
      
 0.499
DEFB130A
Beta-defensin 130A; Antimicrobial host-defense peptide. Has an antiplasmodial activity
      
 0.499
GPX5
Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids
      
 0.473
RGSL1
Regulator of G protein signaling like 1
      
 0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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