STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB37Zinc finger and BTB domain-containing protein 37; May be involved in transcriptional regulation. (503 aa)    
Predicted Functional Partners:
TEX50
Testis-expressed protein 50; Testis expressed 50.
      
 0.642
DARS2
Aspartate--tRNA ligase, mitochondrial; aspartyl-tRNA synthetase 2, mitochondrial.
 
    
 0.619
M0R1W7_HUMAN
Uncharacterized protein.
      
 0.592
CENPL
Centromere protein L; Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
   
 
 0.571
ANKRD45
Ankyrin repeat domain 45.
   
 
 0.541
KIAA0040
Uncharacterized protein KIAA0040; KIAA0040.
   
  
 0.498
RC3H1
Roquin-1; Post-transcriptional repressor of mRNAs containing a conserved stem loop motif, called constitutive decay element (CDE), which is often located in the 3'-UTR, as in HMGXB3, ICOS, IER3, NFKBID, NFKBIZ, PPP1R10, TNF, TNFRSF4 and in many more mRNAs. Cleaves translationally inactive mRNAs harboring a stem-loop (SL), often located in their 3'-UTRs, during the early phase of inflammation in a helicase UPF1-independent manner (By similarity). Binds to CDE and promotes mRNA deadenylation and degradation. This process does not involve miRNAs (By similarity). In follicular helper T (Tf [...]
   
 
 0.462
GK5
Glycerol kinase 5.
   
 
 0.448
THUMPD2
THUMP domain containing 2; Belongs to the methyltransferase superfamily.
      
 0.448
C11orf1
UPF0686 protein C11orf1; Chromosome 11 open reading frame 1.
      
 0.447
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.