node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD10 | C1orf105 | ENSP00000267339 | ENSP00000356700 | Ankyrin repeat domain 10. | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | 0.452 |
C1orf105 | ANKRD10 | ENSP00000356700 | ENSP00000267339 | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | Ankyrin repeat domain 10. | 0.452 |
C1orf105 | CCDC160 | ENSP00000356700 | ENSP00000427951 | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | Coiled-coil domain containing 160; Belongs to the CCDC160 family. | 0.509 |
C1orf105 | FYB2 | ENSP00000356700 | ENSP00000345972 | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | FYN-binding protein 2; Adapter protein that plays a role in T-cell receptor (TCR)- mediated activation of signaling pathways. Required for T-cell activation and integrin-mediated T-cell adhesion in response to TCR stimulation. | 0.479 |
C1orf105 | GOLGA8S | ENSP00000356700 | ENSP00000455298 | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | Golgin A8 family member S; Belongs to the GOLGA8 family. | 0.669 |
C1orf105 | HBP1 | ENSP00000356700 | ENSP00000222574 | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. | 0.512 |
C1orf105 | MTIF2 | ENSP00000356700 | ENSP00000263629 | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.543 |
C1orf105 | NAA50 | ENSP00000356700 | ENSP00000240922 | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear: able to acetylate H4 in vitro, but this result has not been confirmed in vivo. [...] | 0.536 |
C1orf105 | PIGC | ENSP00000356700 | ENSP00000356702 | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis (ECO:0000269|. Belongs to the PIGC family. | 0.608 |
C1orf105 | PPIAL4E | ENSP00000356700 | ENSP00000463419 | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | Peptidyl-prolyl cis-trans isomerase A-like 4E; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. | 0.515 |
C1orf105 | PPIAL4F | ENSP00000356700 | ENSP00000485638 | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | Peptidylprolyl isomerase A like 4F. | 0.590 |
CCDC160 | C1orf105 | ENSP00000427951 | ENSP00000356700 | Coiled-coil domain containing 160; Belongs to the CCDC160 family. | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | 0.509 |
FYB2 | C1orf105 | ENSP00000345972 | ENSP00000356700 | FYN-binding protein 2; Adapter protein that plays a role in T-cell receptor (TCR)- mediated activation of signaling pathways. Required for T-cell activation and integrin-mediated T-cell adhesion in response to TCR stimulation. | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | 0.479 |
GOLGA8S | C1orf105 | ENSP00000455298 | ENSP00000356700 | Golgin A8 family member S; Belongs to the GOLGA8 family. | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | 0.669 |
GOLGA8S | PPIAL4E | ENSP00000455298 | ENSP00000463419 | Golgin A8 family member S; Belongs to the GOLGA8 family. | Peptidyl-prolyl cis-trans isomerase A-like 4E; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. | 0.647 |
GOLGA8S | PPIAL4F | ENSP00000455298 | ENSP00000485638 | Golgin A8 family member S; Belongs to the GOLGA8 family. | Peptidylprolyl isomerase A like 4F. | 0.715 |
HBP1 | C1orf105 | ENSP00000222574 | ENSP00000356700 | HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | 0.512 |
HBP1 | MTIF2 | ENSP00000222574 | ENSP00000263629 | HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. | Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.409 |
HBP1 | NAA50 | ENSP00000222574 | ENSP00000240922 | HMG box-containing protein 1; Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'- TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. | N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. Autoacetylates in vivo. The relevance of N-epsilon-acetyltransferase activity is however unclear: able to acetylate H4 in vitro, but this result has not been confirmed in vivo. [...] | 0.403 |
MTIF2 | C1orf105 | ENSP00000263629 | ENSP00000356700 | Translation initiation factor IF-2, mitochondrial; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Uncharacterized protein C1orf105; Chromosome 1 open reading frame 105. | 0.543 |