CCDC181 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC113	CCDC181	ENSP00000219299	ENSP00000356780	Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation.	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	0.481
CCDC113	FSCB	ENSP00000219299	ENSP00000344579	Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation.	Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.	0.546
CCDC113	PPP1R32	ENSP00000219299	ENSP00000344140	Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation.	Protein phosphatase 1 regulatory subunit 32.	0.632
CCDC181	CCDC113	ENSP00000356780	ENSP00000219299	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation.	0.481
CCDC181	FSCB	ENSP00000356780	ENSP00000344579	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.	0.479
CCDC181	HAPLN3	ENSP00000356780	ENSP00000457180	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding.	0.647
CCDC181	IQCF1	ENSP00000356780	ENSP00000307958	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction.	0.474
CCDC181	OR6S1	ENSP00000356780	ENSP00000313110	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	Olfactory receptor 6S1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	0.548
CCDC181	PPP1R32	ENSP00000356780	ENSP00000344140	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	Protein phosphatase 1 regulatory subunit 32.	0.534
CCDC181	VSTM2B	ENSP00000356780	ENSP00000335038	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	V-set and transmembrane domain containing 2B.	0.487
CCDC181	ZNF439	ENSP00000356780	ENSP00000305077	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	Zinc finger protein 439; May be involved in transcriptional regulation.	0.498
CCDC181	ZNF660	ENSP00000356780	ENSP00000324605	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	Zinc finger protein 660; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.549
CCDC181	ZNF773	ENSP00000356780	ENSP00000282292	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	Zinc finger protein 773; May be involved in transcriptional regulation.	0.547
FSCB	CCDC113	ENSP00000344579	ENSP00000219299	Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.	Coiled-coil domain-containing protein 113; Component of centriolar satellites contributing to primary cilium formation.	0.546
FSCB	CCDC181	ENSP00000344579	ENSP00000356780	Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	0.479
HAPLN3	CCDC181	ENSP00000457180	ENSP00000356780	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding.	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	0.647
HAPLN3	ZNF660	ENSP00000457180	ENSP00000324605	Hyaluronan and proteoglycan link protein 3; May function in hyaluronic acid binding.	Zinc finger protein 660; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.	0.497
IQCF1	CCDC181	ENSP00000307958	ENSP00000356780	IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction.	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	0.474
OR6S1	CCDC181	ENSP00000313110	ENSP00000356780	Olfactory receptor 6S1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	Coiled-coil domain-containing protein 181; Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids. Belongs to the CCDC181 family.	0.548
OR6S1	VSTM2B	ENSP00000313110	ENSP00000335038	Olfactory receptor 6S1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	V-set and transmembrane domain containing 2B.	0.593