node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL1A2 | LUM | ENSP00000297268 | ENSP00000266718 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Lumican; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | 0.999 |
COL1A2 | MOXD1 | ENSP00000297268 | ENSP00000356940 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Monooxygenase DBH like 1. | 0.443 |
CPLX3 | MOXD1 | ENSP00000378464 | ENSP00000356940 | Complexin-3; Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity). Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity). Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity). Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release (By similarity). [...] | Monooxygenase DBH like 1. | 0.548 |
CPLX3 | STX7 | ENSP00000378464 | ENSP00000356918 | Complexin-3; Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity). Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity). Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity). Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release (By similarity). [...] | Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes; Belongs to the syntaxin family. | 0.540 |
LUM | COL1A2 | ENSP00000266718 | ENSP00000297268 | Lumican; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | 0.999 |
LUM | MOXD1 | ENSP00000266718 | ENSP00000356940 | Lumican; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | Monooxygenase DBH like 1. | 0.454 |
MOXD1 | COL1A2 | ENSP00000356940 | ENSP00000297268 | Monooxygenase DBH like 1. | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | 0.443 |
MOXD1 | CPLX3 | ENSP00000356940 | ENSP00000378464 | Monooxygenase DBH like 1. | Complexin-3; Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity). Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity). Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity). Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release (By similarity). [...] | 0.548 |
MOXD1 | LUM | ENSP00000356940 | ENSP00000266718 | Monooxygenase DBH like 1. | Lumican; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. | 0.454 |
MOXD1 | PF4 | ENSP00000356940 | ENSP00000296029 | Monooxygenase DBH like 1. | Platelet factor 4, short form; Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form; Belongs to the intercrine alpha (chemokine CxC) family. | 0.447 |
MOXD1 | SLC18B1 | ENSP00000356940 | ENSP00000275227 | Monooxygenase DBH like 1. | MFS-type transporter SLC18B1; Solute carrier family 18 member B1. | 0.440 |
MOXD1 | SRXN1 | ENSP00000356940 | ENSP00000371388 | Monooxygenase DBH like 1. | Sulfiredoxin-1; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. Belongs to the sulfiredoxin family. | 0.447 |
MOXD1 | STX7 | ENSP00000356940 | ENSP00000356918 | Monooxygenase DBH like 1. | Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes; Belongs to the syntaxin family. | 0.875 |
MOXD1 | TAAR5 | ENSP00000356940 | ENSP00000258034 | Monooxygenase DBH like 1. | Trace amine-associated receptor 5; Olfactory receptor specific for trimethylamine, a trace amine. Also activated at lower level by dimethylethylamine. Trimethylamine is a bacterial metabolite found in some animal odors, and to humans it is a repulsive odor associated with bad breath and spoiled food. This receptor is probably mediated by the G(s)-class of G-proteins which activate adenylate cyclase. | 0.905 |
MOXD1 | TAAR6 | ENSP00000356940 | ENSP00000275198 | Monooxygenase DBH like 1. | Trace amine-associated receptor 6; Orphan receptor. Could be a receptor for trace amines. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. | 0.756 |
MOXD1 | TMEM163 | ENSP00000356940 | ENSP00000281924 | Monooxygenase DBH like 1. | Transmembrane protein 163; May bind zinc and other divalent cations and recruit them to vesicular organelles. | 0.434 |
PF4 | MOXD1 | ENSP00000296029 | ENSP00000356940 | Platelet factor 4, short form; Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form; Belongs to the intercrine alpha (chemokine CxC) family. | Monooxygenase DBH like 1. | 0.447 |
SLC18B1 | MOXD1 | ENSP00000275227 | ENSP00000356940 | MFS-type transporter SLC18B1; Solute carrier family 18 member B1. | Monooxygenase DBH like 1. | 0.440 |
SRXN1 | MOXD1 | ENSP00000371388 | ENSP00000356940 | Sulfiredoxin-1; Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. Belongs to the sulfiredoxin family. | Monooxygenase DBH like 1. | 0.447 |
STX7 | CPLX3 | ENSP00000356918 | ENSP00000378464 | Syntaxin-7; May be involved in protein trafficking from the plasma membrane to the early endosome (EE) as well as in homotypic fusion of endocytic organelles. Mediates the endocytic trafficking from early endosomes to late endosomes and lysosomes; Belongs to the syntaxin family. | Complexin-3; Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion (By similarity). Required for the maintenance of synaptic ultrastructure in the adult retina (By similarity). Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina (By similarity). Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release (By similarity). [...] | 0.540 |