node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD53 | PRAC2 | ENSP00000353796 | ENSP00000484945 | Ankyrin repeat domain-containing protein 53; Required for normal progression through mitosis. Involved in chromosome alignment and cytokinesis via regulation of microtubules polymerization. | PRAC2 small nuclear protein. | 0.418 |
ANKRD53 | TDRD10 | ENSP00000353796 | ENSP00000357465 | Ankyrin repeat domain-containing protein 53; Required for normal progression through mitosis. Involved in chromosome alignment and cytokinesis via regulation of microtubules polymerization. | Tudor domain containing 10. | 0.578 |
PHF20L1 | TDRD10 | ENSP00000378784 | ENSP00000357465 | PHD finger protein 20 like 1. | Tudor domain containing 10. | 0.418 |
PRAC2 | ANKRD53 | ENSP00000484945 | ENSP00000353796 | PRAC2 small nuclear protein. | Ankyrin repeat domain-containing protein 53; Required for normal progression through mitosis. Involved in chromosome alignment and cytokinesis via regulation of microtubules polymerization. | 0.418 |
PRAC2 | TDRD10 | ENSP00000484945 | ENSP00000357465 | PRAC2 small nuclear protein. | Tudor domain containing 10. | 0.594 |
PRAC2 | TMEM132C | ENSP00000484945 | ENSP00000410852 | PRAC2 small nuclear protein. | Transmembrane protein 132C. | 0.526 |
SHE | TDRD10 | ENSP00000307369 | ENSP00000357465 | SH2 domain-containing adapter protein E; Src homology 2 domain containing E. | Tudor domain containing 10. | 0.641 |
TDRD1 | TDRD10 | ENSP00000251864 | ENSP00000357465 | Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of corr [...] | Tudor domain containing 10. | 0.431 |
TDRD1 | TDRD12 | ENSP00000251864 | ENSP00000390621 | Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of corr [...] | Putative ATP-dependent RNA helicase TDRD12; Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary [...] | 0.937 |
TDRD1 | TDRD5 | ENSP00000251864 | ENSP00000406052 | Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of corr [...] | Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity). | 0.432 |
TDRD1 | TDRD9 | ENSP00000251864 | ENSP00000387303 | Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of corr [...] | ATP-dependent RNA helicase TDRD9; ATP-binding RNA helicase required during spermatogenesis. Required to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Acts downstream of piRNA biogenesis: exclusively required for transposon silencing in the nucleus, suggesting that it acts as a nuclear effecto [...] | 0.895 |
TDRD1 | TDRKH | ENSP00000251864 | ENSP00000357812 | Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of corr [...] | Tudor and KH domain-containing protein; Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature [...] | 0.706 |
TDRD10 | ANKRD53 | ENSP00000357465 | ENSP00000353796 | Tudor domain containing 10. | Ankyrin repeat domain-containing protein 53; Required for normal progression through mitosis. Involved in chromosome alignment and cytokinesis via regulation of microtubules polymerization. | 0.578 |
TDRD10 | PHF20L1 | ENSP00000357465 | ENSP00000378784 | Tudor domain containing 10. | PHD finger protein 20 like 1. | 0.418 |
TDRD10 | PRAC2 | ENSP00000357465 | ENSP00000484945 | Tudor domain containing 10. | PRAC2 small nuclear protein. | 0.594 |
TDRD10 | SHE | ENSP00000357465 | ENSP00000307369 | Tudor domain containing 10. | SH2 domain-containing adapter protein E; Src homology 2 domain containing E. | 0.641 |
TDRD10 | TDRD1 | ENSP00000357465 | ENSP00000251864 | Tudor domain containing 10. | Tudor domain-containing protein 1; Plays a central role during spermatogenesis by participating in the repression transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Required for the localization of Piwi proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of corr [...] | 0.431 |
TDRD10 | TDRD12 | ENSP00000357465 | ENSP00000390621 | Tudor domain containing 10. | Putative ATP-dependent RNA helicase TDRD12; Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary [...] | 0.507 |
TDRD10 | TDRD5 | ENSP00000357465 | ENSP00000406052 | Tudor domain containing 10. | Tudor domain-containing protein 5; Required during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity). | 0.526 |
TDRD10 | TDRD9 | ENSP00000357465 | ENSP00000387303 | Tudor domain containing 10. | ATP-dependent RNA helicase TDRD9; ATP-binding RNA helicase required during spermatogenesis. Required to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Acts downstream of piRNA biogenesis: exclusively required for transposon silencing in the nucleus, suggesting that it acts as a nuclear effecto [...] | 0.445 |