STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM229BProtein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family. (80 aa)    
Predicted Functional Partners:
LRCOL1
Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.
      
 0.702
C7orf31
Uncharacterized protein C7orf31; Chromosome 7 open reading frame 31.
      
 0.613
NPIPB9
Nuclear pore complex interacting protein family member B9; Belongs to the NPIP family.
      
 0.571
TMEM60
Transmembrane protein 60.
      
 0.569
SPATA24
Spermatogenesis-associated protein 24; Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis (By similarity).
   
  
 0.554
MAGEE2
Melanoma-associated antigen E2; MAGE family member E2.
      
 0.543
OR2AK2
Olfactory receptor 2AK2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.522
FSCB
Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium.
      
 0.518
IQCF1
IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction.
      
 0.496
CABS1
Calcium-binding and spermatid-specific protein 1; Calcium binding protein, spermatid associated 1.
      
 0.477
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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