LCE1E protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LCE1E

Late cornified envelope protein 1E; Precursors of the cornified envelope of the stratum corneum. (118 aa)

Predicted Functional Partners:

LCE1D

0.997

LCE1B

0.987

LCE1C

0.962

LCE1F

0.903

LCE2C

0.896

LCE1A

0.889

LCE2D

0.872

LCE2B

0.860

LCE3B

0.841

LCE3D

0.826

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LCE1A	LCE1B	ENSP00000334869	ENSP00000353203	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	0.979
LCE1A	LCE1C	ENSP00000334869	ENSP00000475270	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.938
LCE1A	LCE1D	ENSP00000334869	ENSP00000316737	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1D; Precursors of the cornified envelope of the stratum corneum.	0.989
LCE1A	LCE1E	ENSP00000334869	ENSP00000357759	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1E; Precursors of the cornified envelope of the stratum corneum.	0.889
LCE1A	LCE1F	ENSP00000334869	ENSP00000334187	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum.	0.958
LCE1A	LCE2B	ENSP00000334869	ENSP00000357769	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.999
LCE1A	LCE2C	ENSP00000334869	ENSP00000357772	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.	0.990
LCE1A	LCE2D	ENSP00000334869	ENSP00000357773	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum.	0.999
LCE1A	LCE3B	ENSP00000334869	ENSP00000335358	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3B; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens.	0.936
LCE1A	LCE3D	ENSP00000334869	ENSP00000357776	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.773
LCE1B	LCE1A	ENSP00000353203	ENSP00000334869	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	0.979
LCE1B	LCE1C	ENSP00000353203	ENSP00000475270	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1C; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.988
LCE1B	LCE1D	ENSP00000353203	ENSP00000316737	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1D; Precursors of the cornified envelope of the stratum corneum.	0.945
LCE1B	LCE1E	ENSP00000353203	ENSP00000357759	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1E; Precursors of the cornified envelope of the stratum corneum.	0.987
LCE1B	LCE1F	ENSP00000353203	ENSP00000334187	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 1F; Precursors of the cornified envelope of the stratum corneum.	0.902
LCE1B	LCE2B	ENSP00000353203	ENSP00000357769	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.968
LCE1B	LCE2C	ENSP00000353203	ENSP00000357772	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum.	0.925
LCE1B	LCE2D	ENSP00000353203	ENSP00000357773	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum.	0.899
LCE1B	LCE3B	ENSP00000353203	ENSP00000335358	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3B; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens.	0.797
LCE1B	LCE3D	ENSP00000353203	ENSP00000357776	Late cornified envelope protein 1B; Precursors of the cornified envelope of the stratum corneum.	Late cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.814