C1orf68 protein (human) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

C1orf68

Skin-specific protein 32; Chromosome 1 open reading frame 68. (250 aa)

Predicted Functional Partners:

LCE4A

0.851

LCE6A

0.808

LCE2B

0.806

KPRP

0.730

LCE1A

0.665

CRCT1

0.622

FLG2

0.591

TAGAP

0.542

LCE2D

0.533

DSG1

0.519

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1orf68	CRCT1	ENSP00000357764	ENSP00000357779	Skin-specific protein 32; Chromosome 1 open reading frame 68.	Cysteine rich C-terminal 1.	0.622
C1orf68	DSG1	ENSP00000357764	ENSP00000257192	Skin-specific protein 32; Chromosome 1 open reading frame 68.	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.519
C1orf68	FLG2	ENSP00000357764	ENSP00000373370	Skin-specific protein 32; Chromosome 1 open reading frame 68.	Filaggrin-2; Essential for normal cell-cell adhesion in the cornified cell layers. Important for proper integrity and mechanical strength of the stratum corneum of the epidermis. In the N-terminal section; belongs to the S-100 family.	0.591
C1orf68	KPRP	ENSP00000357764	ENSP00000475216	Skin-specific protein 32; Chromosome 1 open reading frame 68.	Keratinocyte proline rich protein.	0.730
C1orf68	LCE1A	ENSP00000357764	ENSP00000334869	Skin-specific protein 32; Chromosome 1 open reading frame 68.	Late cornified envelope protein 1A; Precursors of the cornified envelope of the stratum corneum.	0.665
C1orf68	LCE2B	ENSP00000357764	ENSP00000357769	Skin-specific protein 32; Chromosome 1 open reading frame 68.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.806
C1orf68	LCE2D	ENSP00000357764	ENSP00000357773	Skin-specific protein 32; Chromosome 1 open reading frame 68.	Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum.	0.533
C1orf68	LCE4A	ENSP00000357764	ENSP00000357766	Skin-specific protein 32; Chromosome 1 open reading frame 68.	Late cornified envelope protein 4A; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family.	0.851
C1orf68	LCE6A	ENSP00000357764	ENSP00000411070	Skin-specific protein 32; Chromosome 1 open reading frame 68.	Late cornified envelope protein 6A; Precursors of the cornified envelope of the stratum corneum. Belongs to the LCE family.	0.808
C1orf68	TAGAP	ENSP00000357764	ENSP00000356033	Skin-specific protein 32; Chromosome 1 open reading frame 68.	T-cell activation Rho GTPase-activating protein; May function as a GTPase-activating protein and may play important roles during T-cell activation.	0.542
CRCT1	C1orf68	ENSP00000357779	ENSP00000357764	Cysteine rich C-terminal 1.	Skin-specific protein 32; Chromosome 1 open reading frame 68.	0.622
CRCT1	KPRP	ENSP00000357779	ENSP00000475216	Cysteine rich C-terminal 1.	Keratinocyte proline rich protein.	0.676
CRCT1	LCE2B	ENSP00000357779	ENSP00000357769	Cysteine rich C-terminal 1.	Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum.	0.678
CRCT1	LCE6A	ENSP00000357779	ENSP00000411070	Cysteine rich C-terminal 1.	Late cornified envelope protein 6A; Precursors of the cornified envelope of the stratum corneum. Belongs to the LCE family.	0.460
DSG1	C1orf68	ENSP00000257192	ENSP00000357764	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Skin-specific protein 32; Chromosome 1 open reading frame 68.	0.519
DSG1	FLG2	ENSP00000257192	ENSP00000373370	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Filaggrin-2; Essential for normal cell-cell adhesion in the cornified cell layers. Important for proper integrity and mechanical strength of the stratum corneum of the epidermis. In the N-terminal section; belongs to the S-100 family.	0.885
DSG1	KPRP	ENSP00000257192	ENSP00000475216	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	Keratinocyte proline rich protein.	0.608
FLG2	C1orf68	ENSP00000373370	ENSP00000357764	Filaggrin-2; Essential for normal cell-cell adhesion in the cornified cell layers. Important for proper integrity and mechanical strength of the stratum corneum of the epidermis. In the N-terminal section; belongs to the S-100 family.	Skin-specific protein 32; Chromosome 1 open reading frame 68.	0.591
FLG2	DSG1	ENSP00000373370	ENSP00000257192	Filaggrin-2; Essential for normal cell-cell adhesion in the cornified cell layers. Important for proper integrity and mechanical strength of the stratum corneum of the epidermis. In the N-terminal section; belongs to the S-100 family.	Desmoglein-1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.	0.885
FLG2	KPRP	ENSP00000373370	ENSP00000475216	Filaggrin-2; Essential for normal cell-cell adhesion in the cornified cell layers. Important for proper integrity and mechanical strength of the stratum corneum of the epidermis. In the N-terminal section; belongs to the S-100 family.	Keratinocyte proline rich protein.	0.666