C1orf54 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1orf54	LRRC47	ENSP00000358098	ENSP00000367498	Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54.	Leucine-rich repeat-containing protein 47; Leucine rich repeat containing 47.	0.471
C1orf54	NDST2	ENSP00000358098	ENSP00000310657	Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54.	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan.	0.580
C1orf54	NTN4	ENSP00000358098	ENSP00000340998	Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54.	Netrin-4; May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.	0.428
C1orf54	RBMS2	ENSP00000358098	ENSP00000262031	Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54.	RNA-binding motif, single-stranded-interacting protein 2; RNA binding motif single stranded interacting protein 2.	0.447
LRRC47	C1orf54	ENSP00000367498	ENSP00000358098	Leucine-rich repeat-containing protein 47; Leucine rich repeat containing 47.	Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54.	0.471
LRRC47	RBMS2	ENSP00000367498	ENSP00000262031	Leucine-rich repeat-containing protein 47; Leucine rich repeat containing 47.	RNA-binding motif, single-stranded-interacting protein 2; RNA binding motif single stranded interacting protein 2.	0.442
NDST2	C1orf54	ENSP00000310657	ENSP00000358098	Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Required for the exosomal release of SDCBP, CD63 and syndecan.	Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54.	0.580
NTN4	C1orf54	ENSP00000340998	ENSP00000358098	Netrin-4; May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.	Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54.	0.428
RBMS2	C1orf54	ENSP00000262031	ENSP00000358098	RNA-binding motif, single-stranded-interacting protein 2; RNA binding motif single stranded interacting protein 2.	Uncharacterized protein C1orf54; Chromosome 1 open reading frame 54.	0.447
RBMS2	LRRC47	ENSP00000262031	ENSP00000367498	RNA-binding motif, single-stranded-interacting protein 2; RNA binding motif single stranded interacting protein 2.	Leucine-rich repeat-containing protein 47; Leucine rich repeat containing 47.	0.442