C10orf82 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C10orf82	C9orf135	ENSP00000465712	ENSP00000366402	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Protein C9orf135; Chromosome 9 open reading frame 135.	0.914
C10orf82	CCDC105	ENSP00000465712	ENSP00000292574	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Coiled-coil domain containing 105.	0.916
C10orf82	CFAP52	ENSP00000465712	ENSP00000339449	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.	0.884
C10orf82	EFCAB6	ENSP00000465712	ENSP00000262726	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.	0.883
C10orf82	EFHB	ENSP00000465712	ENSP00000295824	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus.	0.903
C10orf82	FAM166A	ENSP00000465712	ENSP00000344729	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Protein FAM166A; Family with sequence similarity 166 member A.	0.889
C10orf82	PACRG	ENSP00000465712	ENSP00000337946	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease.	0.893
C10orf82	SPAG8	ENSP00000465712	ENSP00000340982	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Sperm-associated antigen 8; Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5- regulated transcriptional activation of CREM isoform tau (By similarity). Involved in the acrosome reaction and in binding of sperm to the zona pellucida (By similarity). Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis. May play a role in fertility and microtubule formation through interaction with RANBP9.	0.883
C10orf82	TEKT2	ENSP00000465712	ENSP00000207457	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.	0.901
C10orf82	TEKT4	ENSP00000465712	ENSP00000295201	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family.	0.905
C9orf135	C10orf82	ENSP00000366402	ENSP00000465712	Protein C9orf135; Chromosome 9 open reading frame 135.	Uncharacterized protein C10orf82; Chromosome 10 open reading frame 82.	0.914
C9orf135	CCDC105	ENSP00000366402	ENSP00000292574	Protein C9orf135; Chromosome 9 open reading frame 135.	Coiled-coil domain containing 105.	0.926
C9orf135	CFAP52	ENSP00000366402	ENSP00000339449	Protein C9orf135; Chromosome 9 open reading frame 135.	Cilia- and flagella-associated protein 52; May play a role in cell growth and/or survival. Belongs to the CFAP52 family.	0.968
C9orf135	EFCAB6	ENSP00000366402	ENSP00000262726	Protein C9orf135; Chromosome 9 open reading frame 135.	EF-hand calcium-binding domain-containing protein 6; Negatively regulates the androgen receptor by recruiting histone deacetylase complex, and protein DJ-1 antagonizes this inhibition by abrogation of this complex.	0.906
C9orf135	EFHB	ENSP00000366402	ENSP00000295824	Protein C9orf135; Chromosome 9 open reading frame 135.	EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus.	0.978
C9orf135	FAM166A	ENSP00000366402	ENSP00000344729	Protein C9orf135; Chromosome 9 open reading frame 135.	Protein FAM166A; Family with sequence similarity 166 member A.	0.894
C9orf135	PACRG	ENSP00000366402	ENSP00000337946	Protein C9orf135; Chromosome 9 open reading frame 135.	Parkin coregulated gene protein; Suppresses cell death induced by accumulation of unfolded Pael receptor (Pael-R, a substrate of Parkin). Facilitates the formation of inclusions consisting of Pael-R, molecular chaperones, protein degradation molecules and itself when proteasome is inhibited. May play an important role in the formation of Lewy bodies and protection of dopaminergic neurons against Parkinson disease.	0.896
C9orf135	SPAG8	ENSP00000366402	ENSP00000340982	Protein C9orf135; Chromosome 9 open reading frame 135.	Sperm-associated antigen 8; Plays a role in spermatogenesis by enhancing the binding of CREM isoform tau to its coactivator FHL5 and increasing the FHL5- regulated transcriptional activation of CREM isoform tau (By similarity). Involved in the acrosome reaction and in binding of sperm to the zona pellucida (By similarity). Plays a role in regulation of the cell cycle by controlling progression through the G2/M phase, possibly by delaying the activation of CDK1 which is required for entry into mitosis. May play a role in fertility and microtubule formation through interaction with RANBP9.	0.937
C9orf135	TEKT2	ENSP00000366402	ENSP00000207457	Protein C9orf135; Chromosome 9 open reading frame 135.	Tektin-2; Structural component of ciliary and flagellar microtubules. Plays a key role in the assembly or attachment of the inner dynein arm to microtubules in sperm flagella and tracheal cilia. Forms filamentous polymers in the walls of ciliary and flagellar microtubules.	0.969
C9orf135	TEKT4	ENSP00000366402	ENSP00000295201	Protein C9orf135; Chromosome 9 open reading frame 135.	Tektin-4; May be a structural component of the sperm flagellum. Contributes to normal sperm motility; Belongs to the tektin family.	0.929