MAB21L3 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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co-expression

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gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGGF1	MAB21L3	ENSP00000316109	ENSP00000358512	Angiogenic factor with G patch and FHA domains 1; Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion.	Protein mab-21-like 3; Mab-21 like 3.	0.961
AHCYL1	MAB21L3	ENSP00000358814	ENSP00000358512	S-adenosylhomocysteine hydrolase-like protein 1; Multifaceted cellular regulator which coordinates several essential cellular functions including regulation of epithelial HCO3(-) and fluid secretion, mRNA processing and DNA replication. Regulates ITPR1 sensitivity to inositol 1,4,5-trisphosphate competing for the common binding site and acting as endogenous 'pseudoligand' whose inhibitory activity can be modulated by its phosphorylation status. In the pancreatic and salivary ducts, at resting state, attenuates inositol 1,4,5-trisphosphate-induced calcium release by interacting with ITP [...]	Protein mab-21-like 3; Mab-21 like 3.	0.624
GASK1A	MAB21L3	ENSP00000407301	ENSP00000358512	Golgi associated kinase 1A; Belongs to the GASK family.	Protein mab-21-like 3; Mab-21 like 3.	0.978
GASK1A	MIPOL1	ENSP00000407301	ENSP00000333539	Golgi associated kinase 1A; Belongs to the GASK family.	Mirror-image polydactyly 1.	0.496
GASK1A	NMNAT3	ENSP00000407301	ENSP00000495112	Golgi associated kinase 1A; Belongs to the GASK family.	Nicotinamide nucleotide adenylyltransferase 3.	0.589
GASK1A	PIGN	ENSP00000407301	ENSP00000492233	Golgi associated kinase 1A; Belongs to the GASK family.	GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation; Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.	0.541
GASK1A	TBC1D8B	ENSP00000407301	ENSP00000349781	Golgi associated kinase 1A; Belongs to the GASK family.	TBC1 domain family member 8B; Involved in vesicular recycling, probably as a RAB11B GTPase- activating protein.	0.405
MAB21L3	AGGF1	ENSP00000358512	ENSP00000316109	Protein mab-21-like 3; Mab-21 like 3.	Angiogenic factor with G patch and FHA domains 1; Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion.	0.961
MAB21L3	AHCYL1	ENSP00000358512	ENSP00000358814	Protein mab-21-like 3; Mab-21 like 3.	S-adenosylhomocysteine hydrolase-like protein 1; Multifaceted cellular regulator which coordinates several essential cellular functions including regulation of epithelial HCO3(-) and fluid secretion, mRNA processing and DNA replication. Regulates ITPR1 sensitivity to inositol 1,4,5-trisphosphate competing for the common binding site and acting as endogenous 'pseudoligand' whose inhibitory activity can be modulated by its phosphorylation status. In the pancreatic and salivary ducts, at resting state, attenuates inositol 1,4,5-trisphosphate-induced calcium release by interacting with ITP [...]	0.624
MAB21L3	GASK1A	ENSP00000358512	ENSP00000407301	Protein mab-21-like 3; Mab-21 like 3.	Golgi associated kinase 1A; Belongs to the GASK family.	0.978
MAB21L3	MB21D2	ENSP00000358512	ENSP00000376246	Protein mab-21-like 3; Mab-21 like 3.	Protein MB21D2; Mab-21 domain containing 2.	0.558
MAB21L3	MIPOL1	ENSP00000358512	ENSP00000333539	Protein mab-21-like 3; Mab-21 like 3.	Mirror-image polydactyly 1.	0.634
MAB21L3	NMNAT3	ENSP00000358512	ENSP00000495112	Protein mab-21-like 3; Mab-21 like 3.	Nicotinamide nucleotide adenylyltransferase 3.	0.595
MAB21L3	PIGN	ENSP00000358512	ENSP00000492233	Protein mab-21-like 3; Mab-21 like 3.	GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation; Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.	0.561
MAB21L3	STAC3	ENSP00000358512	ENSP00000329200	Protein mab-21-like 3; Mab-21 like 3.	SH3 and cysteine-rich domain-containing protein 3; Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membran [...]	0.839
MAB21L3	TBC1D8B	ENSP00000358512	ENSP00000349781	Protein mab-21-like 3; Mab-21 like 3.	TBC1 domain family member 8B; Involved in vesicular recycling, probably as a RAB11B GTPase- activating protein.	0.637
MAB21L3	TMEM212	ENSP00000358512	ENSP00000334072	Protein mab-21-like 3; Mab-21 like 3.	Transmembrane protein 212.	0.632
MB21D2	MAB21L3	ENSP00000376246	ENSP00000358512	Protein MB21D2; Mab-21 domain containing 2.	Protein mab-21-like 3; Mab-21 like 3.	0.558
MIPOL1	GASK1A	ENSP00000333539	ENSP00000407301	Mirror-image polydactyly 1.	Golgi associated kinase 1A; Belongs to the GASK family.	0.496
MIPOL1	MAB21L3	ENSP00000333539	ENSP00000358512	Mirror-image polydactyly 1.	Protein mab-21-like 3; Mab-21 like 3.	0.634