node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FGFR1OP2 | MOB4 | ENSP00000229395 | ENSP00000315702 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | 0.997 |
FGFR1OP2 | PDCD10 | ENSP00000229395 | ENSP00000376506 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). Belongs to the PDCD10 family. | 0.996 |
FGFR1OP2 | SIKE1 | ENSP00000229395 | ENSP00000358541 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | Suppressor of IKBKE 1; Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3- mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways; Belongs to the SIKE family. | 0.997 |
FGFR1OP2 | SLMAP | ENSP00000229395 | ENSP00000499241 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | Sarcolemmal membrane-associated protein; May play a role during myoblast fusion; Belongs to the SLMAP family. | 0.968 |
FGFR1OP2 | STK25 | ENSP00000229395 | ENSP00000325748 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | 0.996 |
FGFR1OP2 | STRIP1 | ENSP00000229395 | ENSP00000358810 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | Striatin-interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. | 0.997 |
FGFR1OP2 | STRIP2 | ENSP00000229395 | ENSP00000249344 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | Striatin-interacting protein 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. Belongs to the STRIP family. | 0.854 |
FGFR1OP2 | STRN | ENSP00000229395 | ENSP00000263918 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | Striatin; Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling; Belongs to the WD repeat striatin family. | 0.892 |
FGFR1OP2 | STRN3 | ENSP00000229395 | ENSP00000350071 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein. | 0.997 |
FGFR1OP2 | STRN4 | ENSP00000229395 | ENSP00000375777 | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | 0.851 |
MOB4 | FGFR1OP2 | ENSP00000315702 | ENSP00000229395 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | FGFR1 oncogene partner 2; May be involved in wound healing pathway; Belongs to the SIKE family. | 0.997 |
MOB4 | PDCD10 | ENSP00000315702 | ENSP00000376506 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). Belongs to the PDCD10 family. | 0.999 |
MOB4 | SIKE1 | ENSP00000315702 | ENSP00000358541 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | Suppressor of IKBKE 1; Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3- mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways; Belongs to the SIKE family. | 0.998 |
MOB4 | SLMAP | ENSP00000315702 | ENSP00000499241 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | Sarcolemmal membrane-associated protein; May play a role during myoblast fusion; Belongs to the SLMAP family. | 0.999 |
MOB4 | STK25 | ENSP00000315702 | ENSP00000325748 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | Serine/threonine-protein kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | 0.999 |
MOB4 | STRIP1 | ENSP00000315702 | ENSP00000358810 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | Striatin-interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. | 0.999 |
MOB4 | STRIP2 | ENSP00000315702 | ENSP00000249344 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | Striatin-interacting protein 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. Belongs to the STRIP family. | 0.999 |
MOB4 | STRN | ENSP00000315702 | ENSP00000263918 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | Striatin; Calmodulin-binding protein which may function as scaffolding or signaling protein and may play a role in dendritic Ca(2+) signaling; Belongs to the WD repeat striatin family. | 0.999 |
MOB4 | STRN3 | ENSP00000315702 | ENSP00000350071 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | Striatin-3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein. | 0.999 |
MOB4 | STRN4 | ENSP00000315702 | ENSP00000375777 | MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family. | Striatin-4; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein; Belongs to the WD repeat striatin family. | 0.999 |