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SLC16A1 protein (human) - STRING interaction network
"SLC16A1" - Solute carrier family 16, member 1 (monocarboxylic acid transporter 1) in Homo sapiens
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SLC16A1Solute carrier family 16, member 1 (monocarboxylic acid transporter 1); Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat di [...] (500 aa)    
Predicted Functional Partners:
BSG
Basigin (Ok blood group); Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes (385 aa)
     
  0.992
SLC16A3
Solute carrier family 16, member 3 (monocarboxylic acid transporter 4); Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity) (465 aa)
         
0.907
SLC16A8
Solute carrier family 16, member 8 (monocarboxylic acid transporter 3); Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity) (504 aa)
         
0.906
SLC18B1
Solute carrier family 18, subfamily B, member 1 (456 aa)
           
  0.783
SLC18A1
Solute carrier family 18 (vesicular monoamine), member 1; Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells (525 aa)
     
   
  0.760
SLC17A1
Solute carrier family 17 (sodium phosphate), member 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane (467 aa)
     
   
  0.694
NDUFS3
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase); Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (264 aa)
       
 
  0.617
CHCHD10
Coiled-coil-helix-coiled-coil-helix domain containing 10; May be involved in the maintenance of mitochondrial organization and mitochondrial cristae structure (142 aa)
       
 
  0.615
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8; Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release (1581 aa)
   
   
  0.608
CISD3
CDGSH iron sulfur domain 3 (127 aa)
       
      0.606
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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