STRINGSTRING
LBX1 protein (human) - STRING interaction network
"LBX1" - Transcription factor LBX1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
LBX1Transcription factor LBX1; Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord; NKL subclass homeoboxes and pseudogenes (281 aa)    
Predicted Functional Partners:
SKOR1
SKI family transcriptional corepressor 1; Acts as a transcriptional corepressor of LBX1 (By similarity). Inhibits BMP signaling; SKI transcriptional corepressors (868 aa)
     
 
  0.931
LHX5
LIM/homeobox protein Lhx5; Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system; LIM class homeoboxes (402 aa)
     
 
  0.785
DPRX
Divergent paired-related homeobox; Putative transcription factor; PRD class homeoboxes and pseudogenes (191 aa)
     
 
  0.780
TPRXL
Tetra-peptide repeat homeobox-like; PRD class homeoboxes and pseudogenes (139 aa)
           
  0.720
TPRX1
Tetra-peptide repeat homeobox protein 1; PRD class homeoboxes and pseudogenes (411 aa)
           
  0.718
DPCD
Protein DPCD; May play a role in the formation or function of ciliated cells (203 aa)
           
  0.711
FBXW4
F-box/WD repeat-containing protein 4; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling; F-box and WD repeat domain containing (412 aa)
           
  0.711
ARGFX
Arginine-fifty homeobox; Putative transcription factor; PRD class homeoboxes and pseudogenes (315 aa)
           
  0.674
GPR153
Probable G-protein coupled receptor 153; Orphan receptor; G protein-coupled receptors, Class A orphans (609 aa)
     
        0.674
LHX1
LIM/homeobox protein Lhx1; Potential transcription factor. May play a role in early mesoderm formation and later in lateral mesoderm differentiation and neurogenesis; LIM class homeoboxes (406 aa)
     
 
  0.658
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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