DIPK1A protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A4GNT	DIPK1A	ENSP00000236709	ENSP00000359333	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity).	Divergent protein kinase domain 1A.	0.524
CCDC126	DIPK1A	ENSP00000304355	ENSP00000359333	Coiled-coil domain containing 126.	Divergent protein kinase domain 1A.	0.527
CCDC126	TMEM219	ENSP00000304355	ENSP00000457492	Coiled-coil domain containing 126.	Insulin-like growth factor-binding protein 3 receptor; Cell death receptor specific for IGFBP3, may mediate caspase- 8-dependent apoptosis upon ligand binding.	0.477
CCDC159	DIPK1A	ENSP00000468232	ENSP00000359333	Coiled-coil domain containing 159.	Divergent protein kinase domain 1A.	0.561
CLEC2D	DIPK1A	ENSP00000261340	ENSP00000359333	C-type lectin domain family 2 member D; Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.	Divergent protein kinase domain 1A.	0.583
DIPK1A	A4GNT	ENSP00000359333	ENSP00000236709	Divergent protein kinase domain 1A.	Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinomas (By similarity).	0.524
DIPK1A	CCDC126	ENSP00000359333	ENSP00000304355	Divergent protein kinase domain 1A.	Coiled-coil domain containing 126.	0.527
DIPK1A	CCDC159	ENSP00000359333	ENSP00000468232	Divergent protein kinase domain 1A.	Coiled-coil domain containing 159.	0.561
DIPK1A	CLEC2D	ENSP00000359333	ENSP00000261340	Divergent protein kinase domain 1A.	C-type lectin domain family 2 member D; Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans.	0.583
DIPK1A	DIPK1B	ENSP00000359333	ENSP00000360757	Divergent protein kinase domain 1A.	Divergent protein kinase domain 1B; Belongs to the DIPK family.	0.666
DIPK1A	DIPK2A	ENSP00000359333	ENSP00000320081	Divergent protein kinase domain 1A.	Divergent protein kinase domain 2A; May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PPI3K-AKT-CDK7 signaling cascade; Belongs to the DIPK family.	0.533
DIPK1A	DIPK2B	ENSP00000359333	ENSP00000381086	Divergent protein kinase domain 1A.	Divergent protein kinase domain 2B.	0.575
DIPK1A	FAM136A	ENSP00000359333	ENSP00000397269	Divergent protein kinase domain 1A.	Protein FAM136A; Family with sequence similarity 136 member A.	0.555
DIPK1A	POMT2	ENSP00000359333	ENSP00000261534	Divergent protein kinase domain 1A.	Protein O-mannosyl-transferase 2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. Belongs to the glycosyltransferase 39 family.	0.682
DIPK1A	TMEM219	ENSP00000359333	ENSP00000457492	Divergent protein kinase domain 1A.	Insulin-like growth factor-binding protein 3 receptor; Cell death receptor specific for IGFBP3, may mediate caspase- 8-dependent apoptosis upon ligand binding.	0.728
DIPK1B	DIPK1A	ENSP00000360757	ENSP00000359333	Divergent protein kinase domain 1B; Belongs to the DIPK family.	Divergent protein kinase domain 1A.	0.666
DIPK1B	DIPK2B	ENSP00000360757	ENSP00000381086	Divergent protein kinase domain 1B; Belongs to the DIPK family.	Divergent protein kinase domain 2B.	0.458
DIPK2A	DIPK1A	ENSP00000320081	ENSP00000359333	Divergent protein kinase domain 2A; May play a role in cardiomyocyte proliferation through paracrine signaling and activation of the PPI3K-AKT-CDK7 signaling cascade; Belongs to the DIPK family.	Divergent protein kinase domain 1A.	0.533
DIPK2B	DIPK1A	ENSP00000381086	ENSP00000359333	Divergent protein kinase domain 2B.	Divergent protein kinase domain 1A.	0.575
DIPK2B	DIPK1B	ENSP00000381086	ENSP00000360757	Divergent protein kinase domain 2B.	Divergent protein kinase domain 1B; Belongs to the DIPK family.	0.458