AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

Fragile X mental retardation syndrome-related protein 2; RNA-binding protein; Belongs to the FMR1 family.

AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Protein FAM50B; Family with sequence similarity 50 member B.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Fragile X mental retardation syndrome-related protein 2; RNA-binding protein; Belongs to the FMR1 family.

AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

Fragile X mental retardation syndrome-related protein 2; RNA-binding protein; Belongs to the FMR1 family.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Guanine nucleotide-binding protein-like 3-like protein; Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal proces [...]

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Protein FAM50B; Family with sequence similarity 50 member B.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Fragile X mental retardation syndrome-related protein 2; RNA-binding protein; Belongs to the FMR1 family.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Guanine nucleotide-binding protein-like 3-like protein; Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal proces [...]

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

E3 ubiquitin-protein ligase LNX; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Nuclear receptor-interacting protein 1; Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. Involved in the regulation of ovarian function (By similarity). Plays a role in renal development.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Retrotransposon-derived protein PEG10; Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'- GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein ( [...]

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Retrotransposon Gag-like protein 4; Involved in cognitive function in the brain, possibly via the noradrenergic system.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Retrotransposon Gag like 9.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Zinc finger protein 250; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.

E3 ubiquitin-protein ligase LNX; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Nuclear receptor-interacting protein 1; Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC. Involved in the regulation of ovarian function (By similarity). Plays a role in renal development.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Retrotransposon-derived protein PEG10; Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'- GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein ( [...]

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.

Retrotransposon Gag-like protein 4; Involved in cognitive function in the brain, possibly via the noradrenergic system.

Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.