node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMCX6 | C10orf62 | ENSP00000444537 | ENSP00000359674 | Protein ARMCX6; May regulate the dynamics and distribution of mitochondria in neural cells; Belongs to the eutherian X-chromosome-specific Armcx family. | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | 0.574 |
ARMCX6 | C1orf189 | ENSP00000444537 | ENSP00000357511 | Protein ARMCX6; May regulate the dynamics and distribution of mitochondria in neural cells; Belongs to the eutherian X-chromosome-specific Armcx family. | Uncharacterized protein C1orf189; Chromosome 1 open reading frame 189. | 0.507 |
ARMCX6 | DRG1 | ENSP00000444537 | ENSP00000329715 | Protein ARMCX6; May regulate the dynamics and distribution of mitochondria in neural cells; Belongs to the eutherian X-chromosome-specific Armcx family. | Developmentally-regulated GTP-binding protein 1; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these mi [...] | 0.429 |
ARMCX6 | OR5M3 | ENSP00000444537 | ENSP00000493070 | Protein ARMCX6; May regulate the dynamics and distribution of mitochondria in neural cells; Belongs to the eutherian X-chromosome-specific Armcx family. | Olfactory receptor 5M3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.475 |
ARMCX6 | PASK | ENSP00000444537 | ENSP00000351475 | Protein ARMCX6; May regulate the dynamics and distribution of mitochondria in neural cells; Belongs to the eutherian X-chromosome-specific Armcx family. | PAS domain-containing serine/threonine-protein kinase; Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in [...] | 0.411 |
ARMCX6 | XAGE5 | ENSP00000444537 | ENSP00000342240 | Protein ARMCX6; May regulate the dynamics and distribution of mitochondria in neural cells; Belongs to the eutherian X-chromosome-specific Armcx family. | X antigen family member 5; Belongs to the GAGE family. | 0.433 |
ARMCX6 | ZNF285 | ENSP00000444537 | ENSP00000464788 | Protein ARMCX6; May regulate the dynamics and distribution of mitochondria in neural cells; Belongs to the eutherian X-chromosome-specific Armcx family. | Zinc finger protein 285; May be involved in transcriptional regulation. | 0.447 |
C10orf62 | ARMCX6 | ENSP00000359674 | ENSP00000444537 | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | Protein ARMCX6; May regulate the dynamics and distribution of mitochondria in neural cells; Belongs to the eutherian X-chromosome-specific Armcx family. | 0.574 |
C10orf62 | C1orf189 | ENSP00000359674 | ENSP00000357511 | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | Uncharacterized protein C1orf189; Chromosome 1 open reading frame 189. | 0.651 |
C10orf62 | DRG1 | ENSP00000359674 | ENSP00000329715 | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | Developmentally-regulated GTP-binding protein 1; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these mi [...] | 0.479 |
C10orf62 | MDFI | ENSP00000359674 | ENSP00000230321 | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | MyoD family inhibitor; Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA- binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the l [...] | 0.549 |
C10orf62 | OR5M3 | ENSP00000359674 | ENSP00000493070 | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | Olfactory receptor 5M3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.604 |
C10orf62 | PASK | ENSP00000359674 | ENSP00000351475 | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | PAS domain-containing serine/threonine-protein kinase; Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in [...] | 0.450 |
C10orf62 | REC114 | ENSP00000359674 | ENSP00000328423 | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | Meiotic recombination protein REC114; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with IHO1/CCDC36 and MEI4, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis; Belongs to the REC114 family. | 0.466 |
C10orf62 | TRAPPC6B | ENSP00000359674 | ENSP00000330289 | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | Trafficking protein particle complex subunit 6B; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic. Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival (Probable). | 0.470 |
C10orf62 | XAGE5 | ENSP00000359674 | ENSP00000342240 | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | X antigen family member 5; Belongs to the GAGE family. | 0.576 |
C10orf62 | ZNF285 | ENSP00000359674 | ENSP00000464788 | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | Zinc finger protein 285; May be involved in transcriptional regulation. | 0.588 |
C1orf189 | ARMCX6 | ENSP00000357511 | ENSP00000444537 | Uncharacterized protein C1orf189; Chromosome 1 open reading frame 189. | Protein ARMCX6; May regulate the dynamics and distribution of mitochondria in neural cells; Belongs to the eutherian X-chromosome-specific Armcx family. | 0.507 |
C1orf189 | C10orf62 | ENSP00000357511 | ENSP00000359674 | Uncharacterized protein C1orf189; Chromosome 1 open reading frame 189. | Uncharacterized protein C10orf62; Chromosome 10 open reading frame 62. | 0.651 |
C1orf189 | DRG1 | ENSP00000357511 | ENSP00000329715 | Uncharacterized protein C1orf189; Chromosome 1 open reading frame 189. | Developmentally-regulated GTP-binding protein 1; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. Appears to have an intrinsic GTPase activity that is stimulated by ZC3H15/DFRP1 binding likely by increasing the affinity for the potassium ions. When hydroxylated at C-3 of 'Lys-22' by JMJD7, may bind to RNA and play a role in translation. Binds to microtubules and promotes microtubule polymerization and stability that are required for mitotic spindle assembly during prophase to anaphase transition. GTPase activity is not necessary for these mi [...] | 0.435 |