node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADNP2 | CBX1 | ENSP00000262198 | ENSP00000377060 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | 0.812 |
ADNP2 | CBX3 | ENSP00000262198 | ENSP00000336687 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the [...] | 0.797 |
ADNP2 | ZNF280C | ENSP00000262198 | ENSP00000360017 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | Zinc finger protein 280C; May function as a transcription factor. | 0.470 |
CBX1 | ADNP2 | ENSP00000377060 | ENSP00000262198 | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | 0.812 |
CBX1 | CBX3 | ENSP00000377060 | ENSP00000336687 | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the [...] | 0.911 |
CBX1 | ZNF280C | ENSP00000377060 | ENSP00000360017 | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | Zinc finger protein 280C; May function as a transcription factor. | 0.568 |
CBX3 | ADNP2 | ENSP00000336687 | ENSP00000262198 | Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the [...] | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | 0.797 |
CBX3 | CBX1 | ENSP00000336687 | ENSP00000377060 | Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the [...] | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | 0.911 |
CBX3 | ZNF280C | ENSP00000336687 | ENSP00000360017 | Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the [...] | Zinc finger protein 280C; May function as a transcription factor. | 0.544 |
CRYBG2 | ZNF280C | ENSP00000428746 | ENSP00000360017 | Beta/gamma crystallin domain-containing protein 2; Crystallin beta-gamma domain containing 2; Belongs to the beta/gamma-crystallin family. | Zinc finger protein 280C; May function as a transcription factor. | 0.418 |
JADE3 | ZNF280C | ENSP00000481850 | ENSP00000360017 | Protein Jade-3; Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. | Zinc finger protein 280C; May function as a transcription factor. | 0.422 |
MPHOSPH8 | ZNF280C | ENSP00000355388 | ENSP00000360017 | M-phase phosphoprotein 8; Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2. Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; [...] | Zinc finger protein 280C; May function as a transcription factor. | 0.497 |
OR4D1 | ZNF280C | ENSP00000493234 | ENSP00000360017 | Olfactory receptor 4D1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Zinc finger protein 280C; May function as a transcription factor. | 0.445 |
SIAE | ZNF280C | ENSP00000263593 | ENSP00000360017 | Sialate O-acetylesterase; Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. | Zinc finger protein 280C; May function as a transcription factor. | 0.450 |
SLC25A43 | ZNF280C | ENSP00000217909 | ENSP00000360017 | Solute carrier family 25 member 43; Belongs to the mitochondrial carrier (TC 2.A.29) family. | Zinc finger protein 280C; May function as a transcription factor. | 0.465 |
TMEM164 | ZNF280C | ENSP00000361138 | ENSP00000360017 | Transmembrane protein 164; Belongs to the TMEM164 family. | Zinc finger protein 280C; May function as a transcription factor. | 0.433 |
ZNF280C | ADNP2 | ENSP00000360017 | ENSP00000262198 | Zinc finger protein 280C; May function as a transcription factor. | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation. | 0.470 |
ZNF280C | CBX1 | ENSP00000360017 | ENSP00000377060 | Zinc finger protein 280C; May function as a transcription factor. | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | 0.568 |
ZNF280C | CBX3 | ENSP00000360017 | ENSP00000336687 | Zinc finger protein 280C; May function as a transcription factor. | Chromobox protein homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the [...] | 0.544 |
ZNF280C | CRYBG2 | ENSP00000360017 | ENSP00000428746 | Zinc finger protein 280C; May function as a transcription factor. | Beta/gamma crystallin domain-containing protein 2; Crystallin beta-gamma domain containing 2; Belongs to the beta/gamma-crystallin family. | 0.418 |