STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C1orf87Uncharacterized protein C1orf87; Chromosome 1 open reading frame 87. (546 aa)    
Predicted Functional Partners:
PIH1D3
Protein PIH1D3; Plays a role in cytoplasmic pre-assembly of axonemal dynein. Belongs to the PIH1 family.
   
    0.620
AKAP14
A-kinase anchor protein 14; Binds to type II regulatory subunits of protein kinase A and anchors/targets them.
   
  
 0.542
STOML3
Stomatin-like protein 3; Required for the function of many mechanoreceptors. Modulate mechanotransduction channels and acid-sensing ion channels (ASIC) proteins. Potentiates PIEZO1 and PIEZO2 function by increasing their sensitivity to mechanical stimulations; Belongs to the band 7/mec-2 family.
   
    0.521
WDR38
WD repeat domain 38.
   
  
 0.518
TEKT1
Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family.
   
    0.495
HEPACAM
Hepatocyte cell adhesion molecule; Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.
    
   0.493
VWA3B
Von Willebrand factor A domain containing 3B.
   
    0.489
FAM216B
Protein FAM216B; Family with sequence similarity 216 member B; Belongs to the FAM216 family.
   
    0.489
TTC29
Tetratricopeptide repeat domain 29.
   
    0.432
CFAP299
Cilia- and flagella-associated protein 299; May be involved in spermatogenesis.
   
    0.426
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.