STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM61Transmembrane protein 61. (210 aa)    
Predicted Functional Partners:
DYDC1
DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis.
      
 0.571
TMEM213
Transmembrane protein 213.
   
  
 0.543
TMEM156
Transmembrane protein 156.
  
   
 0.534
DYDC2
DPY30 domain containing 2; Belongs to the dpy-30 family.
   
  
 0.510
TMEM116
Transmembrane protein 116.
   
  
 0.508
SLC35G2
Solute carrier family 35 member G2; May play a role in cell proliferation.
      
 0.506
RAB42
Ras-related protein Rab-42; RAB42, member RAS oncogene family; Belongs to the small GTPase superfamily. Rab family.
   
  
 0.479
TMEM30B
Cell cycle control protein 50B; Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to th [...]
   
  
 0.445
RTP3
Receptor-transporting protein 3; Promotes functional cell surface expression of the bitter taste receptors TAS2R16 and TAS2R43; Belongs to the TMEM7 family.
      
 0.440
TMEM45B
Transmembrane protein 45B.
   
  
 0.439
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.