node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRTAP9-1 | MCRIP1 | ENSP00000381488 | ENSP00000461433 | Keratin-associated protein 9-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family. | Mapk-regulated corepressor-interacting protein 1; The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition. | 0.443 |
KRTAP9-1 | MROH8 | ENSP00000381488 | ENSP00000339971 | Keratin-associated protein 9-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family. | Protein MROH8; Maestro heat like repeat family member 8. | 0.505 |
KRTAP9-1 | NUTM2G | ENSP00000381488 | ENSP00000361397 | Keratin-associated protein 9-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family. | NUT family member 2G. | 0.518 |
MAP7D2 | NUGGC | ENSP00000368964 | ENSP00000408697 | MAP7 domain containing 2. | Nuclear GTPase SLIP-GC; Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity). | 0.454 |
MAP7D2 | NUTM2G | ENSP00000368964 | ENSP00000361397 | MAP7 domain containing 2. | NUT family member 2G. | 0.590 |
MAP7D2 | RALGPS1 | ENSP00000368964 | ENSP00000259351 | MAP7 domain containing 2. | Ras-specific guanine nucleotide-releasing factor RalGPS1; Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for. | 0.431 |
MAP7D2 | RTL9 | ENSP00000368964 | ENSP00000419786 | MAP7 domain containing 2. | Retrotransposon Gag like 9. | 0.556 |
MCRIP1 | KRTAP9-1 | ENSP00000461433 | ENSP00000381488 | Mapk-regulated corepressor-interacting protein 1; The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition. | Keratin-associated protein 9-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family. | 0.443 |
MCRIP1 | MROH8 | ENSP00000461433 | ENSP00000339971 | Mapk-regulated corepressor-interacting protein 1; The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition. | Protein MROH8; Maestro heat like repeat family member 8. | 0.418 |
MCRIP1 | NUTM2G | ENSP00000461433 | ENSP00000361397 | Mapk-regulated corepressor-interacting protein 1; The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition. | NUT family member 2G. | 0.514 |
MROH8 | KRTAP9-1 | ENSP00000339971 | ENSP00000381488 | Protein MROH8; Maestro heat like repeat family member 8. | Keratin-associated protein 9-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family. | 0.505 |
MROH8 | MCRIP1 | ENSP00000339971 | ENSP00000461433 | Protein MROH8; Maestro heat like repeat family member 8. | Mapk-regulated corepressor-interacting protein 1; The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition. | 0.418 |
MROH8 | NUTM2G | ENSP00000339971 | ENSP00000361397 | Protein MROH8; Maestro heat like repeat family member 8. | NUT family member 2G. | 0.507 |
NUGGC | MAP7D2 | ENSP00000408697 | ENSP00000368964 | Nuclear GTPase SLIP-GC; Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity). | MAP7 domain containing 2. | 0.454 |
NUGGC | NUTM2G | ENSP00000408697 | ENSP00000361397 | Nuclear GTPase SLIP-GC; Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity). | NUT family member 2G. | 0.626 |
NUGGC | RALGPS1 | ENSP00000408697 | ENSP00000259351 | Nuclear GTPase SLIP-GC; Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity). | Ras-specific guanine nucleotide-releasing factor RalGPS1; Guanine nucleotide exchange factor (GEF) for the small GTPase RALA. May be involved in cytoskeletal organization (By similarity). Guanine nucleotide exchange factor for. | 0.476 |
NUGGC | RTL9 | ENSP00000408697 | ENSP00000419786 | Nuclear GTPase SLIP-GC; Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity). | Retrotransposon Gag like 9. | 0.541 |
NUTM2G | KRTAP9-1 | ENSP00000361397 | ENSP00000381488 | NUT family member 2G. | Keratin-associated protein 9-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins (By similarity); Belongs to the KRTAP type 9 family. | 0.518 |
NUTM2G | MAP7D2 | ENSP00000361397 | ENSP00000368964 | NUT family member 2G. | MAP7 domain containing 2. | 0.590 |
NUTM2G | MCRIP1 | ENSP00000361397 | ENSP00000461433 | NUT family member 2G. | Mapk-regulated corepressor-interacting protein 1; The phosphorylation status of MCRIP1 functions as a molecular switch to regulate epithelial-mesenchymal transition. Unphosphorylated MCRIP1 binds to and inhibits the transcriptional corepressor CTBP(s). When phosphorylated by MAPK/ERK, MCRIP1 releases CTBP(s) resulting in transcriptional silencing of the E-cadherin gene and induction of epithelial-mesenchymal transition. | 0.514 |