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GPR107 protein (human) - STRING interaction network
"GPR107" - Protein GPR107 in Homo sapiens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
GPR107Protein GPR107; Involved in Golgi-to-ER retrograde transport. Functions as a host factor required for infection by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT toxins; Belongs to the LU7TM family (600 aa)    
Predicted Functional Partners:
OSTC
Oligosaccharyltransferase complex subunit OSTC; May act as substrate-specific component of the N- oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X- Ser/Thr consensus motif in nascent polypeptide chains. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1; Belongs to the OSTC family (171 aa)
           
  0.725
SCFD1
Sec1 family domain-containing protein 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity) (642 aa)
     
   
  0.692
KDELR1
ER lumen protein-retaining receptor 1; Required for the retention of luminal endoplasmic reticulum resident proteins via vesicular recycling. This receptor recognizes the C-terminal K-D-E-L motif. COPI-coated transport intermediates, either in the form of round vesicles or as tubular processes, mediate retrograde traffic of the KDEL receptor-ligand complexes. Also required for normal vesicular traffic through the Golgi (212 aa)
     
   
  0.676
GPR137C
Integral membrane protein GPR137C; G protein-coupled receptor 137C (429 aa)
           
  0.649
LMX1B
LIM homeobox transcription factor 1-beta; Essential for the specification of dorsal limb fate at both the zeugopodal and autopodal levels; LIM class homeoboxes (406 aa)
           
  0.647
TMEM87B
Transmembrane protein 87B; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN); Belongs to the LU7TM family. TMEM87 subfamily (555 aa)
     
   
  0.645
PUM1
Pumilio homolog 1; Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3’-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5’-UGUANAUA-3’, that is related to the Nanos Response Element (NRE). Mediates post-transcriptional repression of transcripts via different mechanisms- acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation. Also mediates deadenylation-independent repression by promoting accessibility of miRNAs. Following growth fa [...] (1188 aa)
     
   
  0.644
TMEM87A
Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN) (555 aa)
     
   
  0.638
GPR137B
Integral membrane protein GPR137B; G protein-coupled receptor 137B; Belongs to the GPR137 family (399 aa)
           
  0.619
GPR146
Probable G-protein coupled receptor 146; Orphan receptor; G protein-coupled receptors, Class A orphans (333 aa)
           
  0.614
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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