STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZMYND12Zinc finger MYND-type containing 12. (365 aa)    
Predicted Functional Partners:
ARMH2
Armadillo-like helical domain-containing protein 2; Armadillo like helical domain containing 2.
      
 0.654
DYDC1
DPY30 domain-containing protein 1; Plays a crucial role during acrosome biogenesis.
   
  
 0.533
TTC29
Tetratricopeptide repeat domain 29.
   
 
 0.498
CACYBP
Calcyclin-binding protein; May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
      
 0.496
CCDC150
Coiled-coil domain containing 150.
      
 0.480
ZNF497
Zinc finger protein 497; May be involved in transcriptional regulation.
   
  
 0.479
CCDC30
Coiled-coil domain containing 30; Belongs to the prefoldin subunit beta family.
   
  
 0.473
ZNF34
Zinc finger protein 34; May be involved in transcriptional regulation.
   
  
 0.458
LYG1
Lysozyme g1.
   
  
 0.449
SPEF2
Sperm flagellar protein 2; Required for correct axoneme development in spermatozoa. Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein-mediated protein transport during spermatogenesis. Also plays a role in bone growth where it seems to be required for normal osteoblast differentiation.
   
  
 0.438
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.