STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMCO2Transmembrane and coiled-coil domains 2. (182 aa)    
Predicted Functional Partners:
CCDC54
Coiled-coil domain containing 54.
   
  
 0.625
TMCO5A
Transmembrane and coiled-coil domains 5A; Belongs to the TMCO5 family.
   
  
 0.597
C12orf50
Uncharacterized protein C12orf50; Chromosome 12 open reading frame 50.
   
  
 0.565
CCDC187
Coiled-coil domain containing 187.
      
 0.558
CXorf65
Uncharacterized protein CXorf65; Chromosome X open reading frame 65.
   
  
 0.550
OR10T2
Olfactory receptor 10T2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.540
C20orf173
Uncharacterized protein C20orf173; Chromosome 20 open reading frame 173.
   
  
 0.531
FAM209A
Protein FAM209A; Family with sequence similarity 209 member A.
      
 0.526
TEX33
Testis-expressed protein 33; Testis expressed 33.
   
  
 0.505
SHCBP1L
Testicular spindle-associated protein SHCBP1L; Testis-specific spindle-associated factor that plays a role in spermatogenesis. In association with HSPA2, participates in the maintenance of spindle integrity during meiosis in male germ cells.
   
  
 0.498
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.